Results 21 to 30 of about 6,861 (145)

In Vitro Comparison of Device-Induced Hemolysis, Platelet Defects, and von Willebrand Factor Degradation Between the HeartMate 2 and HeartMate 3 Pumps. [PDF]

Artif Organs
This in vitro comparative study demonstrated that the HeartMate 3 pump has a superior overall hemocompatibility profile to the HeartMate 2 pump, underscoring the advantages of the maglev centrifugal pump design compared to the axial pump design. ABSTRACT Background Left ventricular assist devices (LVADs) have been utilized to maintain the circulatory ...
Vandenberge J, Han D, Sun W, Wang S, Tran D, Kim N, Clark K, Perez R, Griffith BP, Wu ZJ.   +9 more
europepmc   +2 more sources

Estudo experimental do uso de um antagonista do receptor da glicoproteína IIb/IIIa das placentas na prevenção de tromboses em microanastomoses vasculares An experimental study on the use of an antagonist of the platelet glycoprotein IIb/IIIa receptor in the prevention of thrombosis in vascular microanastomoses

Acta Ortopédica Brasileira, 2000
O autor comparou, experimentalmente, a eficácia da droga abciximab, um antagonista do receptor da glicoproteína IIb/IIIa das plaquetas, na prevenção da trombose nas microanastomoses arteriais em ratos Wistar.
Márcio Issamu Oide
doaj   +1 more source

Bleeding Disorders in Children With Genetic Diseases: A Narrative Review

Acta Paediatrica, EarlyView.
ABSTRACT Aim The lack of data on bleeding risk assessment in children with genetic diseases is concerning given their increased care needs and risk of haemorrhagic complications compared to the general population. Identification of haemostatic disorders is crucial for implementing preventive measures and mitigating bleeding risk.
Raphaelle Cagol, Mariam Sbeity Barakat, Marjolaine Willems, Tasnime Akbaraly, Biron‐Andreani Christine, Isabelle Diaz, Alexandre Theron   +6 more
wiley   +1 more source

Comparison of Blood Cell Count Results Between MgSO4 and K2EDTA. Stability and Accuracy of Platelet Counting With MgSO4

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction We investigated the stability and accuracy of platelets with MgSO4 and compared the results of blood counts between MgSO4 and K2EDTA. Methods Platelet stability as a function of time was assessed on the XN Sysmex analyzer by comparing the percentage deviation to the desirable bias of the EFLM.
Michel Soulard, Hela Ketatni, Pascale Croix, Soraya Wuilleme, Patrick Cohen   +4 more
wiley   +1 more source

Rapid anti‐HPA‐1a antibody quantification with a Luminex bead‐based assay: A method evaluation

Vox Sanguinis, EarlyView.
Abstract Background and Objectives High concentration of human platelet antigen‐1a (HPA‐1a) antibodies is reported to be associated with severe foetal and neonatal alloimmune thrombocytopaenia (FNAIT). The gold standard for quantification of anti‐HPA‐1a antibodies is the monoclonal antibody immobilization of platelet antigen (MAIPA) assay, which is a ...
Klara Asplund Högelin, Emöke Deschmann, Petter Höglund, Agneta Wikman   +3 more
wiley   +1 more source

Inherited human gp91phox deficiency is associated with impaired isoprostane formation and platelet dysfunction [PDF]

, 2011
Platelet isoprostane 8-ISO-prostaglandin F2α (8-iso-PGF2α), a proaggregating molecule, is believed to derive from nonenzymatic oxidation of arachidonic acid.
Bartimoccia, S, Carnevale, R, Di Santo, S, Finocchi, A, Lenti, L, Mendolicchio, L, Pignatelli, P, Plebani, A, Sanguigni, V, Soresina, A, Violi, F   +10 more
core   +1 more source

Platelet Glycoprotein lib: Chromosomal Localization and Tissue Expression [PDF]

, 1987
The GPIIb-IIIa complex functions as a receptor for cytoadhesive proteins on the platelet surface. Both GPIIb and GPIIIa are synthesized by a human erythroleukemia (HEL) cell line.
Bray, Paul F, Cook, Richard G, Johnston, Geoffrey I, Kan, Yuet Wai, Lau, Chris, McEver, Rodger P, Rosa, Jean-Philippe, Shiu, Donny T, Shuman, Marc A   +8 more
core   +1 more source

The role of platelet microvesicles in intercellular communication. [PDF]

, 2016
In recent years, there has been exponential growth in the interest in microvesicles, which is reflected by the number of publications. Initially referred to as platelet dust by Peter Wolf in 1967, platelet microvesicles (PMV) are now recognized as ...
Edelstein, Leonard C.
core   +2 more sources

Receptor‐Dependent and ‐Independent Effects of Hemin on Platelet Plasma Membrane Disintegration

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Microhemorrhages lead to the release of erythrocytes, which are then degraded and lysed. These hemolyses result in the liberation of free iron‐containing hemin. Hemin induces platelet activation and ferroptosis. Inhibition of GPVI/CLEC‐2 receptor‐mediated ITAM‐signaling inhibits hemin‐induced platelet activation (low hemin concentrations). Deferoxamine,
Zoi Laspa, Anne‐Katrin Rohlfing, Ravi Hochuli, Pamela Weronika Sowa, Tatsiana Castor, Meinrad Paul Gawaz   +5 more
wiley   +1 more source

Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]

, 2005
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen, Heeschen C, James SK, Khaliq A, Luttun A, Mak KH   +5 more
core   +1 more source