Results 21 to 30 of about 6,659 (141)
Platelets: Novel Biomaterials for Cancer Diagnosis and Therapeutic Delivery
MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.Platelets, particularly tumor‐educated platelets (TEPs), play a crucial role in cancer diagnosis and treatment. TEPs undergo molecular changes in RNA and protein profiles, making them valuable biomarkers for diagnosis, prognosis, and monitoring. In nanomedicine, platelets serve as drug carriers in tumor‐targeted nanomaterials, enhancing specificity and
Xin Wang, Jie Chen, Hubing Shi
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Health Science Reports, Volume 8, Issue 4, April 2025.ABSTRACT Background Atherosclerosis is the leading cause of cardiovascular disease (CVD). Historically, the management of atherosclerosis was focused on decreasing lipid profile levels; however, recent evidence demonstrated that platelets and leukocytes play an important role in forming and exacerbating atherosclerosis.
Ali Mortezaei +7 more
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Journal of Extracellular Vesicles, Volume 14, Issue 4, April 2025.ABSTRACT There is growing interest in the role of extracellular vesicles (EVs) in neonatal pathology. This study aimed to characterise circulating EVs following preterm birth. This single‐centre prospective observational study included cord and postnatal plasma from preterm (n = 101) and full‐term infants (n = 66).
Claire A. Murphy +13 more
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International Journal of Nanomedicine, 2015 Jianhui Wu,1 Yuji Wang,1 Yaonan Wang,1 Ming Zhao,1,2 Xiaoyi Zhang,1 Lin Gui,1 Shurui Zhao,1 Haimei Zhu,1 Jinghua Zhao,1 Shiqi Peng11Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Endogenous Prophylactic
Wu J +9 more
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Association of Anaesthetists guidelines: the use of blood components and their alternatives
Anaesthesia, Volume 80, Issue 4, Page 425-447, April 2025.Summary Background The administration of blood components and their alternatives can be lifesaving. Anaemia, bleeding and transfusion are all associated with poor peri‐operative outcomes. Considerable changes in the approaches to optimal use of blood components and their alternatives, driven by the findings of large randomised controlled trials and ...
Akshay Shah +12 more
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Engineered Platelets for Cancer Therapy
Aggregate, Volume 6, Issue 2, February 2025.This review explores the intricate crosstalk between platelets and immune cells within the tumor microenvironment and provides a comprehensive summary of the various types of engineered platelets designed to inhibit tumor growth and prevent postoperative tumor recurrence and metastasis.
Kai Zhang +5 more
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Alzheimer's &Dementia, Volume 21, Issue 2, February 2025.Abstract Tauopathy is one of the pathological features of Alzheimer's disease and related dementias (ADRD). At present, there have been many studies on the formation, deposition, and intercellular transmission of tau in neurons and immune cells. The vasculature is an important component of the central nervous system.
Chuyao Huang +6 more
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Disseminated intravascular coagulation: cause, molecular mechanism, diagnosis, and therapy
MedComm, Volume 6, Issue 2, February 2025.DIC course: imbalance of coagulative system, anticoagulant activity, and fibrinolysis system. DIC includes two phenotypes: thrombotic and fibrinolytic. The thrombotic phenotype includes coagulation activation, insufficient anticoagulation, and hypofibrinolysis, indicating a proclivity for clot formation.
Fangchen Gong +7 more
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How to explain the beneficial effects of platelet‐rich plasma
Periodontology 2000, Volume 97, Issue 1, Page 95-103, February 2025.Abstract Platelet‐rich plasma (PRP) is the platelet and leukocyte‐containing plasmatic fraction of anticoagulated autologous blood. While evidence supporting the clinical use of PRP in dentistry is low, PRP is widely used in sports medicine, orthopedics, and dermatology. Its beneficial activity is commonly attributed to the growth factors released from
Reinhard Gruber
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