Results 31 to 40 of about 6,861 (145)
NADPH oxidase 2 (NOX2): a key target of oxidative stress-mediated platelet activation and thrombosis [PDF]
, 2018 Oxidative stress represents an imbalance between the production of reactive oxygen species (ROS) and the cellular antioxidant system. Increased levels of oxidative stress contribute to the development of atherosclerosis that eventually leads to ...
Fuentos, Eduardo +3 more
core +1 more source
Case Reports in Medicine, Volume 2026, Issue 1, 2026.Background Oxaliplatin is widely used in the treatment of gastrointestinal tumors but is associated with rare adverse effects, including immune thrombocytopenia. The incidence of oxaliplatin‐associated immune thrombocytopenia (OIIT) may be frequently overlooked due to its rarity, and in some cases, it can be difficult to treat.
Jian Zheng +5 more
wiley +1 more source
Folia Histochemica et Cytobiologica, 2010 Abciximab (Abci) and eptifibatide (Epti) are antiaggregate drugs which may reduce thrombotic complications inacute coronary syndromes. The aim of this work was the investigation of the interaction between the phospholipid-GPIIb/IIIa glycoprotein complex ...
Ewa Gorodkiewicz +2 more
doaj
Mediators of Inflammation, Volume 2026, Issue 1, 2026.Severe acute pancreatitis (SAP) is associated with high morbidity and mortality. Microcirculatory dysfunction is a critical pathological event in this process and a primary contributor to organ failure (OF). Despite the pivotal role of P‐selectin in mediating the adhesion of activated platelets and leukocytes to the vascular endothelium, a process ...
Yali Liu +10 more
wiley +1 more source
Molecular Nutrition &Food Research, Volume 69, Issue 24, December 2025.Nuts and legumes contain both nutrients and bioactive compounds supporting cardiovascular health related to influencing DNA methylation. These foods are related to reducing oxidative stress, supplying methyl donors, and modulating genes involved in platelet function, such as PEAR1 and mitochondrial genes, in association with helping reduce inflammation
Siwaphorn Chaimati +2 more
wiley +1 more source
Selatogrel: Potential to redefine timely anti‐platelet intervention
British Journal of Pharmacology, Volume 182, Issue 22, Page 5435-5452, November 2025.Acute coronary syndrome (ACS) encompasses a number of heart diseases that cause a sudden decrease in coronary perfusion, precipitating cardiomyocyte necrosis or heightened risk thereof. This pathology is a major burden of cardiovascular disease.
Rudy N. Zalzal +3 more
wiley +1 more source
Glycoprotein IIb-IIIa Is Expressed on Avian Multilineage Hematopoietic Progenitor Cells [PDF]
, 1999 Updated information and services can be found ...
Beat A. Imhof +5 more
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Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy
Advanced NanoBiomed Research, Volume 5, Issue 10, October 2025.This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai +5 more
wiley +1 more source
The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence
Brain and Behavior, Volume 15, Issue 10, October 2025.This study delineates the multiple pathways leading to stroke, encompassing genetic risk factors such as lipid/cholesterol metabolism, blood pressure regulation genes, and endothelial dysfunction. The report includes genetic pathways such as Val66Met polymorphism, prothrombin G20210A, interleukin‐6 and tumor necrosis factor gene variant, along with ...
Mega Obukohwo Oyovwi +3 more
wiley +1 more source
Molecular basis for Staphylococcus aureus-mediated platelet aggregate formation under arterial shear in vitro. [PDF]
, 2008 OBJECTIVE: Staphylococcus aureus is the most frequent causative organism of infective endocarditis (IE) and is characterized by thrombus formation on a cardiac valve that can embolize to a distant site. Previously, we showed that S.
Clarke, Niamh +5 more
core