Results 131 to 140 of about 863,280 (291)
Introduction: Erectile dysfunction (ED) is a prevalent condition with a multifactorial etiology, including vascular, endocrine, neurological, and psychological factors.
Samuel Rexy Adrianto Tondohusodo +6 more
doaj +1 more source
Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen +10 more
wiley +1 more source
Zitao Zhang,1 Yuanhui Ji,2 Zhen Wang,1 Xusheng Qiu,1 Yixin Chen1 1Department of Orthopedics, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China; 2Department of Clinical Laboratory, The Affiliated Drum Tower ...
Qiu X, Zhang Z, Chen Y, Ji Y, Wang Z
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Relationship between platelet indices and spontaneous echo contrast in patients with mitral stenosis
Aims To determine the association of platelet indices with spontaneous echo contrast (SEC) in patients with mitral ...
KAYA, Mustafa +23 more
core +1 more source
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen +13 more
wiley +1 more source
Giovanetti, Thayse Vanessa +2 more
openaire +4 more sources
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu +5 more
wiley +1 more source
Indices of platelet activation and the stability of coronary artery disease
AIM: To determine whether indices of platelet activation are associated with the stability of coronary artery disease (CAD). METHODS: Platelet function was examined in 677 consecutive aspirin-treated patients presenting for cardiac catheterization ...
Frelinger, Andrew L. III +7 more
core +1 more source
Leveraging the critical role of glutathione (GSH) in mediating drug resistance and scavenging reactive oxygen species (ROS) in cancer cells, a carrier‐free GSH‐consuming theranostic nanoprodrug, consisting of a BODIPY photosensitizer and the chemotherapeutic drug paclitaxel linked through a GSH‐consuming drug linker, is developed to deeply explore the ...
Hansheng Huang, Binglin Sui
wiley +1 more source
Role of Platelet Indices in Differentiating the Causes of Thrombocytopenia in a Tertiary Care Hospital [PDF]
BACKGROUND: Thrombocytopenia is defined as platelet counts below 1,50,000 cells/cu.mm, but they do not reveal the underlying pathology which could be either hypoproductive or hyperdestructive etiology. This study attempts to find the usefulness of these
Keerthy Aberna, A
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