Results 51 to 60 of about 48,919 (253)

The serum lipid profiles in immune thrombocytopenia: Mendelian randomization analysis and a retrospective study

Thrombosis Journal, 2023
Background Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease characterized by increased platelet destruction and impaired thrombopoiesis. The changes in platelet indices depend on the morphology and volume of platelets. Serum lipids have
Pengcheng Xu, Shouqing Han, Ming Hou, Yajing Zhao, Miao Xu   +4 more
doaj   +1 more source

Evaluation of factors affecting the quantity and quality of platelet-rich plasma and platelet-derived growth factor-BB

CHRISMED Journal of Health and Research, 2021
Context: Platelet-rich plasma (PRP) releases growth factors (GFs) upon activation which accelerates the healing and regeneration in the target tissue. Wider applications of PRP warrant product standardization.
Rahul Verma, Priyanka Sharma, Gita Negi, Abhishek Kandwal, Harish Chandra   +4 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

PLATELET INDICES: INDICATORS OF DIABETIC RETINOPATHY PLATELET INDICES AS NEW BIOMARKERS IN PATIENTS OF DIABETIC RETINOPATHY

International Journal of Advanced Research
Aim and Objectives: The aim of this study is to study role of platelet indices in type 2 diabetes mellitus (T2DM) with and without diabetic retinopathy. The objectives included assessing platelet count, mean platelet volume (MPV), platelet distribution width (PDW), and platelet large cell ratio(P-LCR)within these patient categories and to comparing ...
Shefali Mittal, Suparna Dubey, Jyoti Jyoti, Jl Goyal, Charu Charu   +4 more
openaire   +1 more source

A correlation between platelet indices and preeclampsia

Hematology, Transfusion and Cell Therapy, 2019
Preeclampsia is one of the major health problems causing maternal morbidity and mortality, complicating 3-8% of pregnancies. It has been suggested that the alterations in the coagulation and fibrinolysis play a role in the pathogenesis of preeclampsia. The markers of platelet activation include platelet count, platelet distribution width, mean platelet
Thalor, Nitesh, Singh, Kanika, Pujani, Mukta, Chauhan, Varsha, Agarwal, Charu, Ahuja, Rashmi   +5 more
openaire   +4 more sources

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Correlation of platelet count and platelet indices with neonatal sepsis-diagnostic and prognostic indicator

Pediatric Review: International Journal of Pediatric Research, 2017
Introduction: To evaluate variations in platelet count and platelet indices- mean platelet volume (MPV) and platelet distribution width (PDW) in neonatal sepsis. Methodology: This study was conducted over a period of one year in Neonatal Intensive Care Unit of Mata Chanan Devi Hospital, New Delhi.
Dr. Dilipkumar Choudhary, Dr. Ajay Kumar Tiwari, Dr.Subhash Narang, Dr. Jatin Chhabra   +3 more
openaire   +2 more sources

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Utility of Platelet Count and Platelet Indices in the Evaluation of Thrombocytopenia

Journal of Evidence Based Medicine and Healthcare, 2020
BACKGROUND Thrombocytopenia is defined as a low platelet count, less than 150000 / microlitre which is attributed to a variety of haematological and pathological disorders. It can result from four different mechanisms like hypoproduction, hyperdestruction, abnormal platelet distribution and dilutional loss.
Tejaswi Peddaverannagari, Nalinimohan Chakkirala, Shailaja Prabhala, Ashokkumar Deshpande   +3 more
openaire   +1 more source