Results 81 to 90 of about 863,280 (291)

Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]

, 2002
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Day, S., Chaudhry, M.A., Muriithi, E.W., Belcher, P.R.   +3 more
core   +5 more sources

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Platelet Count and Platelet Indices as Predictive Markers of COVID-19 Mortality. [PDF]

Physiol Res
The aim of the study was to analyze changes in platelet count and function in hospitalized COVID-19 patients and compare them with non-COVID-19 patients, focusing on the association between platelet indices and mortality beyond the known link between neutrophil-to-lymphocyte ratio (NLR) and COVID-19 severity. The study sample consisted of 572 patients,
Kozelová Z, Jarčušková D, Tomčo L, Lacková L, Kozárová Z, Valiková Bavoľárová M, Rušinová L, Kozárová M.   +7 more
europepmc   +3 more sources

Assessment of bronchial asthma exacerbation: the utility of platelet indices

The Egyptian Journal of Bronchology, 2020
Background Activated platelets and platelet indices have a vital role in bronchial hyper-responsiveness, bronchoconstriction, bronchial inflammation, airway remodeling, angiogenesis, allergic reactions, and repair and renewal of tissues; platelets ...
Manal R. Hafez, Hoda A. Eid, Sawsan B. Elsawy, Nehad Emad Eldin, Asmaa A. El Madbouly   +4 more
doaj   +1 more source

Utility of Platelet Count and Platelet Indices in the Evaluation of Thrombocytopenia

Journal of Evidence Based Medicine and Healthcare, 2020
BACKGROUND Thrombocytopenia is defined as a low platelet count, less than 150000 / microlitre which is attributed to a variety of haematological and pathological disorders. It can result from four different mechanisms like hypoproduction, hyperdestruction, abnormal platelet distribution and dilutional loss.
Tejaswi Peddaverannagari, Nalinimohan Chakkirala, Shailaja Prabhala, Ashokkumar Deshpande   +3 more
openaire   +1 more source

Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the treatment effect of anticoagulation versus antiplatelet therapy in patients ...
Elena Badillo Goicoechea, Patrick Ellsworth, James E. Siegler, James R. Brorson, Christina M. Lineback, Frank G. Conyers, Deborah Kerrigan, Kelsey Eklund, Shadi Yaghi, Farid Khasiyev, Emiliya Melkumova, Collin J. Culbertson, Marissa D'Souza, Dinesh V. Jillella, Patrick Glover, Hassan Aboul‐Nour, Fadi Nahab, Mahan Shahrivari, Simona Nedelcu, David S. Liebeskind, Matthew M. Smith, Aaron Rothstein, Anna Bowman, Alicia Zha, Narendra Kala, Ahmad Abu Qdais, Sami Al Kasab, Mudassir Farooqui, Diana Rojas‐Soto, Yasmin Aziz, Franziska Herpich, Jean‐Philippe Daniel, Sean L. Thompson, Vivek Patel, Thanh N. Nguyen, Siddharth Sehgal, Wenzheng Yu, Wayneho Kam, Russel Van Coevering, Oana M. Dumitrascu, Muhammad Alvi, Balaji Krishnaiah, Setareh Salehi Omran, Guillermo Linares, Eesha Singh, Hamid Ali, Mary Penckofer, Jesse M. Thon, Shani Mannion, Dalia Chahien, Lucia Chen, Fawad Talat, Mehdi Abbasi, Richa Sharma   +53 more
wiley   +1 more source

Platelet indices as an acute phase reactant

Journal of Pediatric Critical Care, 2019
Objective: Objectives: To investigate in children with febrile illness the correlation between Platelet Indices and C reactive protein (CRP) Methods: Descriptive study which included 400 children over one year admitted with febrile illness.
Kalyani Pillai, Sarika Premarajan, V K Parvathy   +2 more
doaj   +1 more source

Mimicking platelet indices in patients with malaria and dengue hemorrhagic fever: characteristics and clinical applications

Tropical Medicine and Health, 2022
Background Although platelet indices are routinely available using automated blood cell counters, the clinical applications of these parameters for malaria and dengue hemorrhagic fever (DHF) have not been substantially implemented.
Nant The Su Mon, Noppadon Tangpukdee, Prakaykaew Charunwatthana, Kobporn Boonnak, Srivicha Krudsood, Shigeyuki Kano, Polrat Wilairatana, Wattana Leowattana   +7 more
doaj   +1 more source

Evaluation of platelet indices as markers of tuberculosis among children in India [PDF]

Children with tuberculosis have increased platelet count and platelet/lymphocyte ratio along with decreased mean platelet volume, suggesting that these indices may be useful as adjunct tools in diagnosis of paediatric tuberculosis https://bit.ly ...
Prendergast, AJ, B, B, Venkataraman, A, Thiruvengadam, K, S, E, M, K, S, S, Hanna, LE, Smuk, M, J, NH, Balaji, S, Smuk, Melanie, Nancy Hilda, J, B, Brindha, S, Subha, Balaji, Sarath, Luke, Hanna Elizabeth, Nancy Hilda J, Hanna, Luke Elizabeth, J, Nancy Hilda, Melanie Smuk, Prendergast, Andrew J., S, Elilarasi, Kannan Thiruvengadam, Aishwarya Venkataraman, Luke Elizabeth Hanna, Sarath Balaji, M, Karthick, Subha S, Elilarasi S, Brindha B, Andrew J. Prendergast, Karthick M, Venkataraman, Aishwarya, Thiruvengadam, Kannan   +34 more
core   +1 more source

The platelet indices in pediatric patients with acute appendicitis [PDF]

, 2017
Background: The diagnosis of Acute Appendicitis (AA) remains a problem in pediatric population. It has been suggested that Mean Platelet Volume (MPV) is lower in the patients with AA.
Yılmaz, Yunus, Arslan, Hasan, Gümüşdere, Musa, Kara, Fatih, Üstebay, Sefer   +4 more
core   +1 more source