Results 71 to 80 of about 1,561,237 (278)

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

Advanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu, Wen Zhang, Lunxin Liu, Lan Gui, Yumei Qin, Xiaohui Yang, Longjian Zhang, Chaohua Wang, Jinpeng Hu, Gaoyang Guo, Qing Jiang, Jin Wang, Li Yang, Bo Zhang, Yunbing Wang   +14 more
wiley   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source

Positive effect of platelet rich fibrin on osseointegration

Medicina Oral Patología Oral y Cirugia Bucal, 2016
Leukocyte-platelet rich fibrin (L-PRF) is a second generation platelet concentrate clinically used to accelerate tissue healing and bone regeneration. Achieving reduced implant osseointegration time could provide immediate or early loading of implants.
Öncü, Elif, Bayram, Burak, Kantarcı, Alpdoğan, Gülsever, Serap, Alaaddinoğlu, Emine-Elif   +4 more
openaire   +2 more sources

Antibacterial and Antifungal Efficacy of Platelet-Rich Fibrin and Platelet-Rich Fibrin Matrix against Root Canal Microflora

Journal of Pharmacy and Bioallied Sciences, 2021
Background: Binding of such proteins with a developing fibrin mesh or to the extracellular matrix has the ability to create chemotactic gradients aiding the recruitment of stem cells, thereby, stimulating cell migration and differentiation this may promotes repair and regeneration.
Pinky Singh, Subhra Dey, Vinisha Pandey, Arora Abhas, Suprabha Sharan, Neetu Kharat   +5 more
openaire   +3 more sources

Atlas‐Guided CD55‐Enriched Neutrophil Extracellular Vesicles for Complement–Macrophage Modulation in Diabetic Wounds

Advanced Science, EarlyView.
ABSTRACT Diabetic wounds are characterized by persistent inflammation and impaired immune resolution, yet the therapeutic translation of single‐cell atlases into rational immunomodulatory strategies remains limited. Here, integration of diabetic‐wound single‐cell transcriptomic datasets identifies a neutrophil subpopulation enriched in cluster of ...
Tairong Cui, Jieying Li, Jibing He, Jia Wang, Yun Qian, Yilin Jin, Liuqing Yang, Zaijin Tao, Ziyun Li, Zhengsheng Chen, Wenjing Wang, Xin Ma, Jinglei Wu   +12 more
wiley   +1 more source

Use of Platelet-Rich Fibrin in Hypospadias Surgery

Journal of the Scientific Society, 2023
Abstract Hypospadias is a common congenital anomaly. Treatment for hypospadias is surgical, but there is no technique that is recognized as the gold standard. The most common complication occurring after hypospadias repair is urethrocutaneous fistula with a reported incidence varying from 4% to 28%.
Rajendra B Nerli, S Rangrez, C Saniya
openaire   +2 more sources

Evaluation of Fibrin Network Pattern Changes of Platelet Rich Fibrin and Titanium Prepared Platelet Rich Fibrin of Individuals With and Without Periodontitis: A Cell Block Cytology [PDF]

, 2019
INTRODUCTION: Platelet Rich Fibrin is a polymerized fibrin matrix in a tetra molecular structure with > 97% of the platelets, cytokines, leukocytes & circulating stem cells. Titanium prepared platelet-rich fibrin (T-PRF) has stronger and thicker fibrin
Abarnashree, A R
core  

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

Platelet rich fibrin (PRF) and β -Tricalcium phosphate with coronally advanced flap for the management of grade-II furcation defect [PDF]

, 2014
BACKGROUND: Multirooted teeth offer unique and challenging problems due to the furcation area, creates situations in which routine periodontal procedures are somewhat limited and special procedures are generally required.CASE DETAIL: The present case was
Rohit, R, Shalabh, M, Sambhav, J, Ranjana, M   +3 more
core   +1 more source

Injection of Leukocyte‐Poor Platelet‐Rich Plasma During Rotator Cuff Repair Can Increase Healing Rate but Does Not Affect Clinical Outcomes: A Systematic Review and Meta‐analysis of Randomized Controlled Trials

Arthroscopy, EarlyView.
Purpose To evaluate the efficacy of injected leukocyte‐poor platelet‐rich plasma (LP‐PRP) during arthroscopic rotator cuff repair, primarily in reducing failure rates and, secondarily, in improving shoulder function and clinical outcome. Methods A systematic review was performed in accordance with the Preferred Reporting Items for Systematic Review and
Charalampos Pitsilos, Dimitrios Rigkos, Byron Chalidis   +2 more
wiley   +1 more source