Results 311 to 320 of about 269,308 (373)

Impact of autologous platelet-rich plasma used for treatment of oligozoospermia in dogs on the quality of semen and testicular blood flow. [PDF]

Vet Res Commun
Mohamed A, Fathi M, Shamaa AA, El Shahat KH.   +3 more
europepmc   +1 more source

High‐throughput screen identifies MAS9 as a novel inhibitor of the C‐type lectin receptor‐2 (CLEC‐2)–podoplanin interaction

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The C‐type lectin‐like receptor‐2 (CLEC‐2) is a platelet receptor for the endogenous ligand podoplanin. This interaction contributes to several (patho)physiological processes, such as lymphangiogenesis, preservation of blood and lymphatic vessel integrity organ development, and tumour metastasis.
Marcin A. Sowa, Yan Wu, Jan van Groningen, Ying Di, Helma van den Hurk, Johannes A. Eble, Jonathan M. Gibbins, Ángel García, Alice Y. Pollitt   +8 more
wiley   +1 more source

Comprehensive single-cell transcriptome analysis of autologous platelet-rich plasma therapy on human thin endometrium. [PDF]

Sci Rep
Zeng J, Quan J, Liu H, Geng W, Qiu F, Liu J.   +5 more
europepmc   +1 more source

Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and high‐throughput RNA sequencing

British Journal of Pharmacology, EarlyView.
Background and Purpose Nimodipine, an L‐type voltage‐gated calcium channel blocker, is an approved cerebral vasorelaxant. We hypothesized that nimodipine attenuates the pro‐inflammatory shift in microglial phenotypes. Here, we analysed the effects of nimodipine on morphological and functional microglial phenotypes as well as their transcriptomic ...
István Pesti, Valentin Varga, Erda Qorri, Rita Frank, Diana Kata, Krisztián Vinga, Péter Archibald Szarvas, Ákos Menyhárt, Károly Gulya, Ferenc Bari, Eszter Farkas   +10 more
wiley   +1 more source

The efficacy of platelet-rich plasma in ankle disease: a systematic review and meta-analysis. [PDF]

J Orthop Surg Res
Ding Q, Wang X, Liu Y, Li Y, Zhang D, Wang H, Ma S, Han Q, Zhuang W.   +8 more
europepmc   +1 more source

Role of the RAB27/SYTL Axis in Tumor Microenvironment Construction

Cancer Science, EarlyView.
This review focuses on the role of the RAB27/SYTL axis in various cancer types associated with tumor microenvironment modifications. The importance of this pathway and the potential therapeutic strategies targeting vesicle production for the treatment of cancer are also discussed.
Miwa Tanaka, Takuro Nakamura
wiley   +1 more source

Cord Blood Platelet-Rich Plasma in Cesarean Section Wound Management. [PDF]

Obstet Gynecol Int
Thanachaiviwat A, Suthaporn S, Teng-Umnuay P.   +2 more
europepmc   +1 more source

Efficacy of Platelet-Rich Plasma Injection in the Management of Lateral Epicondylitis: A Retrospective Assessment. [PDF]

Cureus
Alzahrani OH, Alenezi G, Alsagri M, Alzahrani OH, Alhussain S, Alfayyadh JM, Alzahrani A, Alrashidi W, Almogbil IH, Altasan A.   +9 more
europepmc   +1 more source

Mesenchymal Stem Cell‐Derived Exosomes: A Promising Therapeutic Strategy for Age‐Related Diseases

Cell Proliferation, EarlyView.
Mechanisms of MSC‐Exos in the treatment of age‐related diseases. A Immunomodulatory and anti‐inflammatory, MSC‐Exos mediate immunomodulatory and anti‐inflammatory effects by regulating the polarisation of T cells and macrophages, promoting an anti‐inflammatory state while inhibiting pro‐inflammatory responses; B Suppression of oxidative stress, MSC ...
Bohua Wei, Mengting Wei, Haonan Huang, Ting Fan, Zhichang Zhang, Xiaoyu Song   +5 more
wiley   +1 more source

Blood flow restriction-enhanced platelet-rich plasma: A pilot randomised controlled trial protocol. [PDF]

J Exp Orthop
Ayyan M, Alladaboina S, Al-Dolaymi A, Boudier-Revéret M, Papakostas E, Marín Fermín T.   +5 more
europepmc   +1 more source