Results 261 to 270 of about 81,782 (305)

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan, Candace L. Doepker, Gregory P. Brorby   +2 more
wiley   +1 more source

Intracranial pressure, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, C-reactive protein, and D-dimer mortality predictors in isolated severe traumatic brain injury. [PDF]

Surg Neurol Int
Wardhana DPW, Wahyudana ING, Putra KK, Sebayang SES, Satyarsa ABS, Maliawan S, Mahadewa TGB.   +6 more
europepmc   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Xin'an Jianpi Tongbi formulation improves self-perception of patient and reduces platelet-to-lymphocyte ratio in rheumatoid arthritis: A cohort study. [PDF]

Medicine (Baltimore)
Liu S, Liu J, Cheng X, Fang D, Chen X, Zhang X, Ding X.   +6 more
europepmc   +1 more source

Age‐related clinical heterogeneity and peripheral T cell profile alterations in primary Sjögren's disease: A retrospective study of 5778 patients

Rheumatology &Autoimmunity, EarlyView.
This large‐scale retrospective study of 5778 primary Sjögren's disease (SjD) patients, stratified by diagnostic age, defines a distinct clinical and immunological profile for early‐diagnosed (<45 years) disease. We identified early diagnosis as an independent risk factor for hypergammaglobulinemia and interstitial lung disease, underpinned by a ...
Yuan Ning, Ruiling Feng, Kai Zhang, Yipeng Han, Ruoyi Wang, Guangwen Li, Yuebo Jin, Jing He   +7 more
wiley   +1 more source

Combination of red blood cell distribution width and platelet-to-lymphocyte ratio for predicting severity of diabetic retinopathy. [PDF]

Int J Ophthalmol
Wei ZM, Zhao Y, Ding RR, Zeng YS, Zeng Z, He ZT, Hao J, Hu JJ, Yu JG, You CY.   +9 more
europepmc   +1 more source

Predicting Failure at Initiation of High‐Flow Nasal Oxygen in Patients With COVID‐19: Literature Review, Development and Internal Validation of a Prediction Model

Respirology, EarlyView.
A prediction model was developed for high‐flow nasal oxygen (HFNO) failure in acute hypoxemic patients with COVID‐19 pneumonia using predictors available prior to HFNO initiation. This stable and good‐performing model can assist in clinical decision‐making at a critical point, aiding timely intervention for patients at risk of HFNO failure.
Daphne J. T. Sjauw, Matthijs L. Janssen, Yasemin Türk, Carmen A. T. Reep, Leo Heunks, Sara J. Baart, Evert‐Jan Wils, on behalf of the Dutch HFNO study group, NORMO2 project group, E. J. Wils, H. Endeman, W. Hanselaar, M. L. Janssen, Y. Türk, R. A. S. Hoek, R. Heller, D. P. Boer, J. H. Elderman, A. Dubois, O. Hoiting, J. Holters, M. vd Steen‐Dieperink, L. Heunks, E. J. Wils, S. J. Baart, M. L. Duiverman, L. M. Fleuren, L. C. Urlings‐Strop, J. G. van den Aardweg, D. Weller, C. A. T. Reep, D. J. T. Sjauw   +31 more
wiley   +1 more source

The Platelet-to-Lymphocyte Ratio (PLR) as a Non-Invasive Biomarker for Cervical Malignancy in Conization Patients. [PDF]

Life (Basel)
Kalas N, Szabó V, Vida B, Tóth Z, Lőczi L, Sebők B, Merkely P, Lintner B, Ács N, Keszthelyi A, Várbíró S, Tóth R, Keszthelyi M.   +12 more
europepmc   +1 more source

Interactive effects of platelet-to-lymphocyte ratio and FIB-4 index for risk stratification of liver fibrosis in metabolic dysfunction-associated steatotic liver disease: performance assessment comparing interactive models with traditional composite scores. [PDF]

Front Med (Lausanne)
Shi M, Zhang G, Zhou H, Li Y, Hou Y, Yang X, Liu L, Tong G.   +7 more
europepmc   +1 more source

Baseline platelet-to-lymphocyte ratio is associated with severe immune effector cell-associated toxicities in diffuse large B-cell lymphoma patients receiving anti-CD19 CAR T-cell therapy. [PDF]

Front Immunol
Kim C, Kwak K, Kang KW, Park Y, Kim BS, Choi YS.   +5 more
europepmc   +1 more source