Massive blood transfusion following older adult trauma: The effect of blood ratios on mortality
Abstract Background Massive blood transfusion (MBT) following older adult trauma poses unique challenges. Despite extensive evidence on optimal resuscitative strategies in the younger adult patients, there is limited research in the older adult population.
Rae D. Hohle+5 more
wiley +1 more source
Modern concepts of the platelet in health and disease [PDF]
Thesis (M.D.)--Boston ...
Estes, J. Worth
core
Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]
Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien+6 more
core +2 more sources
THROMBOPATHIC THROMBOCYTOPENIA: SUCCESSFUL TRANSFUSION OF BLOOD PLATELETS [PDF]
Erwin O. Hirsch+2 more
openalex +1 more source
Platelet transfusion for cancer secondary thrombocytopenia: Platelet and cancer cell interaction
Chemoradiotherapy and autoimmune disorder often lead to secondary thrombocytopenia in cancer patients, and thus, platelet transfusion is needed to stop or prevent bleeding. However, the effect of platelet transfusion remains controversial for the lack of
Juan Wang+3 more
doaj
Study of Transfused Platelets in a Case of Congenital Hypoplastic Thrombocytopenia [PDF]
A. D. Bell+3 more
openalex +1 more source
Predicting postpartum haemorrhage: A systematic review of prognostic models
Background Postpartum haemorrhage (PPH) remains a leading cause of maternal mortality and morbidity worldwide, and the rate is increasing. Using a reliable predictive model could identify those at risk, support management and treatment, and improve maternal outcomes.
Bethany L. Carr+5 more
wiley +1 more source
Transfusion: Predict the Next Token and Diffuse Images with One Multi-Modal Model [PDF]
We introduce Transfusion, a recipe for training a multi-modal model over discrete and continuous data. Transfusion combines the language modeling loss function (next token prediction) with diffusion to train a single transformer over mixed-modality sequences.
arxiv
Confetti Ordering by Polymer Brushes [PDF]
I consider the ordering of dilute platelet additives when incorporated into an end-grafted polymer brush. The competition between wetting interactions and the anisotropic stress environment of the interior of the brush causes these platelet additives to either remain suspended at the outer edge of the brush laying flat against the brush surface (as ...
arxiv
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner+7 more
wiley +1 more source