Results 141 to 150 of about 107,646 (331)

Characterization of ADA‐GEL Based Hydrogels Combined with Mesoporous Bioactive Glass Nanoparticles (MBGNs) and Human Platelet Lysate (HPL) for 3D (Bio)Printing

Macromolecular Materials and Engineering, EarlyView.
Alginate dialdehyde (ADA)‐gelatin (GEL) hydrogels are supplemented with mesoporous bioactive glass nanoparticles (MBGNs) and human platelet lysate (HPL) to enhance the biological performance of 3D printed scaffolds. Improved printability and higher shape fidelity are observed by incorporating 0.1% (w/v) MBGNs.
Yijun Zhao, Faina Bider, Aldo R. Boccaccini   +2 more
wiley   +1 more source

Impact of HLA antigen and antibody expression on cross-matching and transfusion effect

Zhongguo shuxue zazhi
[Objective] To study the relationship between the expression intensity of HLA-Ⅰ platelet antibodies in patients with platelet transfusion refractoriness (PTR) and platelet cross-matching, and to further evaluate other factors in order to provide relevant
HE Honghong, CHENG Jing, WANG Yihan, JIANG Min, TANG Longhai   +4 more
doaj   +1 more source

Refining Platelet Purification Methods: Enhancing Proteomics for Clinical Applications [PDF]

arXiv
Background: Platelet proteomics offers valuable insights for clinical research, yet isolating high-purity platelets remains a challenge. Current methods often lead to contamination or platelet loss, compromising data quality and reproducibility. Objectives: This study aimed to optimize a platelet isolation technique that yields high-purity samples ...
arxiv  

HLA-matched platelet transfusion therapy of severe aplastic anemia [PDF]

, 1978
G Tosato, FR Applebaum, AB Deisseroth
openalex   +1 more source

Analysis of Late Complications Associated With Hematopoietic Stem Cell Transplantation in Patients With Dyskeratosis Congenita

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Dyskeratosis congenita (DKC) is a genetic disorder frequently complicated by bone marrow failure (BMF). Hematopoietic stem cell transplantation (HSCT) remains the only curative treatment option for BMF in DKC. However, late complications of DKC, especially pulmonary fibrosis (PF), pose significant challenges.
Takashi Koike, Shohei Yamamoto, Mayuko Shibata, Kohei Otsuka, Yumiko Sugishita, Ryota Kaneko, Naoko Kawabata, Sachio Fujita, Kosuke Akiyama, Daisuke Toyama, Miharu Yabe, Atsushi Uchiyama, Hiromasa Yabe   +12 more
wiley   +1 more source

Effect of HLA-A, -B functional epitope mismatch on platelet transfusions in patients with hematological diseases

Zhongguo shuxue zazhi
Objective To investigate the impact of human leukocyte antigen (HLA) functional epitope mismatch (EM) on the efficacy of platelet transfusion in patients with hematological diseases.
Lu YU, Yunlei HE, Yiwen HE, Shuangyue LI, Chunxiao CHEN, Gang DENG   +5 more
doaj   +1 more source

Rejection of marrow from DLA-identical canine littermates given transfusions before grafting: antigens involved are expressed on leukocytes and skin epithelial cells but not on platelets and red blood cells [PDF]

, 1979
Rainer Storb, PL Weiden, H. Joachim Deeg, TC Graham, K Atkinson, SJ Slichter, ED Thomas   +6 more
openalex   +1 more source

Ponatinib‐related gelatinous transformation of the bone marrow

eJHaem, EarlyView.
Stefano Lazzi, Brunangelo Falini
wiley   +1 more source

Pharmacotherapy for Cirrhosis in Japan

Portal Hypertension &Cirrhosis, EarlyView.
As cirrhosis progresses from the compensated to the decompensated stage, liver disease‐related events such as varices, ascites, encephalopathy, sarcopenia, jaundice, and bleeding tendency, as well as liver carcinogenesis, can occur at a high rate. With the advent of new pharmacotherapies for cirrhosis in the last decade, liver fibrosis has been shown ...
Hiroki Nishikawa, Soo Ki Kim, Akira Asai
wiley   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source