Results 171 to 180 of about 130,828 (352)
Safety and effectiveness of the combination of 5‐azacitidine and ruxolitinib in VEXAS syndrome: A single‐centre experience
British Journal of Haematology, EarlyView.Gregorio Maria Bergonzi, Enrico Cozzo, Alessandro Tomelleri, Costanza Piccolo, Gianluca Scorpio, Carmelo Gurnari, Francesca Romano, Marco Matucci‐Cerinic, Lorenzo Dagna, Massimo Bernardi, Luca Vago, Fabio Ciceri, Corrado Campochiaro, Elisa Diral +13 morewiley +1 more sourceRepeated injection of pooled frozen allogeneic umbilical cord blood mesenchymal stromal cells in 5 flat‐racing horses
Equine Veterinary Education, EarlyView.Summary Background
Tendinopathies in racehorses are challenging to treat, and restoring normal tendon composition remains elusive despite extensive research. Equine multipotent mesenchymal stromal cells (MSC) have shown promise for tendon repair, and various sources of MSC have been described.A. Merchan Muñoz, N. Coté, T. Koch, S. Mehrpouyan, A. H. Alizadeh, K. A. Russell, G. Monteith, J. Koenig +7 morewiley +1 more sourceTGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation
The FEBS Journal, EarlyView.TGFβ stimulation promotes EMT in MCF7 cells, increasing their ability to bind, activate, and aggregate PLT. This effect involves the upregulation of adhesion molecules Integrin‐αv and Galectin‐3. Inhibiting Integrin‐αv or Galectin‐3, through Cilengitide and GB1103, reduces PLT adhesion to MCF7 and PLT aggregation, suggesting a mechanism linking TGFβ ...Margherita Genitoni, Lucia Merolle, Agnese Razzoli, Eleonora Maurizi, Gaia Gavioli, Roberto Baricchi, Chiara Marraccini, Davide Schiroli +7 morewiley +1 more sourceWhat Laboratory Tests and Physiologic Triggers Should Guide the Decision to Administer a Platelet or Plasma Transfusion in Critically Ill Children and What Product Attributes Are Optimal to Guide Specific Product Selection? From the Transfusion and Anemia EXpertise Initiative–Control/Avoidance of Bleeding
, 2022 Meghan Delaney, Oliver Karam, Lani Lieberman, Katherine Steffen, Jennifer A. Muszynski, Ruchika Goel, Scot T. Bateman, Robert I. Parker, Marianne E. Nellis, Kenneth E. Remy +9 moreopenalex +2 more sourcesInternational Practices in Managing Preconception, Pregnancy and Childbirth in Women With Glanzmann Thrombasthenia: A Survey From the European Association of Haemophilia and Allied Disorders (EAHAD)
Haemophilia, EarlyView.ABSTRACT Background
Glanzmann thrombasthenia (GT) is an inherited platelet disorder resulting in severely reduced platelet aggregation and increased bleeding tendency. Pregnancy and childbirth in women with GT present significant challenges for both mother and child.Karlijn H. G. Rutten, Roger E. G. Schutgens, Roseline d'Oiron, Mathieu Fiore, Giancarlo Castaman, Keith Gomez, Mary Mathias, Michelle Lavin, Petra Elfvinge, Rezan Abdul Kadir, Karin P. M. van Galen, the Glanzmann Thrombasthenia and Women and Girls with Bleeding Disorders Working Groups of the EAHAD +11 morewiley +1 more sourcePediatric Plasma and Platelet Transfusions on Extracorporeal Membrane Oxygenation: A Subgroup Analysis of Two Large International Point-Prevalence Studies and the Role of Local Guidelines*
, 2019 Marianne E. Nellis, Arun Saini, Philip C. Spinella, Peter J. Davis, Marie E. Steiner, Marisa Tucci, Melissa M. Cushing, Pierre Demaret, Simon Stanworth, Stéphane Leteurtre, Oliver Karam +10 moreopenalex +2 more sources