Results 171 to 180 of about 374,751 (237)

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada   +7 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao   +5 more
wiley   +1 more source

A new inverse trigonometric shear deformation theory for isotropic and functionally graded sandwich plates [PDF]

open access: yesComposites Part B: Engineering, 2014
A new inverse trigonometric shear deformation theory is proposed for the static, buckling and free vibration analyses of isotropic and functionally graded (FG) sandwich plates.
Trung-Kien Nguyen   +2 more
exaly   +2 more sources
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Plate Tectonics

Science, 1972
Plate tectonics as a theory distinct from, yet embracing, continental drift and sea floor spreading was formulated by Wilson [1965] when he described a continuous network of ridges, transforms, and subduction zones bounding large rigid plates. Wilson explicitly discussed many of the consequences of the relative motion of torsionally rigid plates such ...
openaire   +3 more sources

Kirchhoff Plates

2020
In the present chapter finite element implementation of Kirchhoff plates in bending is discussed using the so-called conforming and not conforming Hermite shape functions. Note that Hermite shape functions other than more common Lagrange functions, that consider nodal parameters only, use more kinematic parameters than the ones representing the ...
Ferreira A. J. M., Fantuzzi N.
openaire   +2 more sources

Laminated Plates

2020
In this chapter we consider a first order shear deformation theory for the static, free vibration and buckling analysis of laminated plates. We introduce a computation of the shear correction factor and solve some examples with MATLAB codes. The main difference between the present chapter and the previous one related to Mindlin plates is that due ...
Ferreira A. J. M., Fantuzzi N.
openaire   +2 more sources

Plating for ACDF

Surgical Neurology, 2002
Abstract RE: Portnoy HD. Anterior cervical discectomy and fusion. Surg Neurol 2001;56:178–80.
openaire   +2 more sources

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