Results 241 to 250 of about 3,387,841 (331)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Identifying Volar Locking Plates on Plain Radiographs: Can Artificial Intelligence Models 'Beat' Clinicians? [PDF]

Cureus
Albert A, Nicholls A, Avis D, Zekry M, Arsan M, Saha P, Stoneham A.   +6 more
europepmc   +1 more source

Densitometric Quantitation of Platelet Activating Factor and Other Phospholipids in Human Saliva Using Enzyme Reaction on a Silica Plate

, 1994
Chiyo Matsubara, Takuji Ohyama, K Takamura   +2 more
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Contemporary Evolution of an At-Risk Stickleback Population During a Severe Drought. [PDF]

Evol Appl
Sanderson S, Eckert L, Barrett RDH, Reimchen TE, Hendry AP.   +4 more
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Investigation on Damage and Energy Absorption Performance of Aluminum Foam Sandwich Plates Under Low-Velocity Impact. [PDF]

Materials (Basel)
Guo K, Zhu Y, Zhou S, Zhu L.
europepmc   +1 more source

Experimental investigation on the web stability of plate girders

, 1960
Ka-ching Wong
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Mechanistic Transformation of CuI Nanoparticles Into Oxidation-Resistant 2D Copper Nanoplates. [PDF]

Small
Han HJ, Yang MY, Lee C, Jin G, Hart JL, Mutheu R, Lee HI, Kim SH, Jang H, Kim M, Jung YS, Goddard WA, Cha JJ, Choi C.   +13 more
europepmc   +1 more source