Results 271 to 280 of about 3,387,841 (331)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Agreement of Clinical Grade and Laboratory Grade Force Plates for Countermovement Jump Metrics in Youth Athletes. [PDF]

Int J Sports Phys Ther
Greenberg E, Greenberg E, Riesenberg J, Graci V, Ulman S.   +4 more
europepmc   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Investigating insulin's role in regulating local aromatase in growth plate development. [PDF]

PLoS One
Hu S, Xue M, Dong Y, Li C, Qiao L, Zheng R.   +5 more
europepmc   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Retrograde Intramedullary Nailing Versus Locked Plating for Periprosthetic Distal Femur Fractures: A Propensity-matched Cohort from TriNetX. [PDF]

J Orthop Case Rep
Shahzad A, Ali HB, Chohan H, Kaddour-Hocine F, Shoaib A, Pandor I.   +5 more
europepmc   +1 more source

Two dimensional configuration analysis of a flat-plate solar collector

, 1975
Prabhakar P. Rao
openalex   +1 more source

Protocol for systematic screening of histone H3/H4 mutants to identify histone residues critical for BCAA-dependent replicative lifespan. [PDF]

STAR Protoc
Park S, Liu Y, Ahn SH.
europepmc   +1 more source

Antimicrobial susceptibility testing of <i>Aggregatibacter Actinomycetemcomitans</i> can be performed using the EUCAST medium for anaerobic bacteria. [PDF]

J Oral Microbiol
Jensen AB, Matuschek E, Kahlmeter G, Nørskov-Lauritsen N.   +3 more
europepmc   +1 more source