Results 71 to 80 of about 282,490 (270)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Research of Security as a Service for VMs in IaaS Platform

IEEE Access, 2018
With the rapid promotion and application of cloud computing technology in various fields, cloud computing security has become the focus of attention.
Xueyuan Yin, Xingshu Chen, Lin Chen, Guolin Shao, Hui Li, Shusong Tao   +5 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

ANALISIS PERBANDINGAN LAYANAN DBMS ANTARA SQL SERVER DI MICROSOFT AZURE SEBAGAI PLATFORM AS A SERVICE DENGAN SQL SERVER [PDF]

, 2018
SQL Server adalah sistem manajemen basis data relasional Microsoft (RDBMS). SQL Server sekarang dapat di-host sepenuhnya di Microsoft Azure, baik dalam mesin virtual host (VM) atau sebagai layanan host.
Ririn Dwi Agustin, DS, Tio Gelar Pamungkas, 123040053   +1 more
core  

Autonomic Cloud Computing: Open Challenges and Architectural Elements

, 2012
As Clouds are complex, large-scale, and heterogeneous distributed systems, management of their resources is a challenging task. They need automated and integrated intelligent strategies for provisioning of resources to offer services that are secure ...
Buyya, Rajkumar, Calheiros, Rodrigo N., Li, Xiaorong   +2 more
core   +1 more source

UAV digital platform for first-response operations, daily transports, and data acquisition

Developments in the Built Environment
The use of unmanned aircraft vehicles (UAVs) for various tasks and services has increased significantly in recent years. One of the most important application areas is first-response missions, which UAVs can enhance by speeding up both resource ...
Julia Harttunen, David Hästbacka, Harry Edelman, Joel Stenroos, Marko Kauppinen, Juha Röning   +5 more
doaj   +1 more source

M2M Platform-as-a-Service for sustainability governance

2012 Fifth IEEE International Conference on Service-Oriented Computing and Applications (SOCA), 2012
Recently, cloud computing technologies have been employed for large-scale machine-to-machine (M2M) systems, as they could potentially offer better solutions for managing monitoring data and analytics applications to support the needs of different consumers.
Hong-Linh Truong, Schahram Dustdar
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source