Results 71 to 80 of about 3,679,625 (294)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
CGIAR Genebank Platform - Plan of Work and Budget 2021 [PDF]
, 2021 The most important output of the Genebank Platform is the availability and provision of healthy, viable, documented germplasm from the 35 crop and tree collections managed by the CGIAR, which are maintained, and safety duplicated, in long-term ...
CGIAR Genebank Platform
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
International Journal of Online and Biomedical Engineering (iJOE), 2012 This paper reports on a first step towards the implementation of a framework for remote experimentation of electric machines â?? the RemoteLabs platform. This project was focused on the development of two main modules: the user Web-based and the electric machines interfaces.
Nils Crabeel +2 more
openaire +4 more sources
Understanding of Digital Transformation and Its Background
Maketingu Janaru, 2020 Recent evolutions in technology have enabled the rapid growth of digital companies through ecosystems, which have generated both threats and opportunities for existing companies who are struggling to adapt themselves to this rapidly changing environment.
Norio Imai
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Journal of Medical Science, 2014 “UnderstAID” is a platform that helps informal caregivers to understand and aid their demented relatives. It is an international project initiated by Denmark, Poland and Spain.
Elżbieta Skorupska +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
New England Journal of Medicine, 2021 The RECOVERY Platform Sharon-Lise Normand provides a biostatistician’s view of the preliminary findings on dexamethasone for Covid-19, noting that the results represent an important step and that t...
openaire +2 more sources
CGIAR Platform for Big Data in Agriculture - Plan of Work and Budget 2021 [PDF]
, 2021 The CGIAR Platform for Big Data in Agriculture is a cross-cutting program of the global CGIAR consortium of non-profit research institutes looking into virtually every aspect of food security spanning: genomics, breeding, agroecology, climate science ...
CGIAR Platform for Big Data in Agriculture
core +2 more sources