Results 141 to 150 of about 5,361,118 (283)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Design and Experimental Validation of a Flexible-Hinge-Based Manual Mechanism for Micro/Nano-Displacement Scaling. [PDF]

Micromachines (Basel)
Tian S, Gao M, Fu Y, Fang C, Deng X, Cui L.   +5 more
europepmc   +1 more source

Development of a Simulation Platform for ROV systems

, 2015
Sigrid Marie Mo
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Long-term disability after initiation of platform versus high-efficacy disease-modifying therapy in relapsing-onset multiple sclerosis. [PDF]

J Neurol
Guo J, Olsson T, Johansson E, Alfredsson L, Hedström AK.   +4 more
europepmc   +1 more source

IMMERSION : a platform for visualization and temporal analysis of email data

, 2014
Deepak Jagdish
openalex   +1 more source

Balancing Revenue Streams in Online Video Platforms: The Impact of Original Content Provision on Business Model Selection

Zhuoning Zhang, Zhongsheng Hua
openalex   +2 more sources

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Cooperation mode selection and information sharing in a live streaming e-commerce supply chain with traffic data investment. [PDF]

PLoS One
Wang H, Zhu A, Yu L, Mu D, Meng Z.
europepmc   +1 more source

NexusCore – AI Enhanced SaaS Platform Exploring Innovations in Intelligent Cloud Solutions

Reetika Raut, Avantika Sutar
openalex   +2 more sources