Results 101 to 110 of about 3,641,296 (294)

CGIAR GENDER Impact Platform [PDF]

open access: yes, 2022
GENDER puts equality at the forefront of global agricultural research for development, both within and beyond CGIAR, to kickstart a process of genuine change toward greater gender equality, improved opportunities for youth and social inclusion.
CGIAR GENDER Impact Platform
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

An optimized framework for processing multicentric polysomnographic data incorporating expert human oversight

open access: yesFrontiers in Neuroinformatics
IntroductionPolysomnographic recordings are essential for diagnosing many sleep disorders, yet their detailed analysis presents considerable challenges.
Benedikt Holm   +16 more
doaj   +1 more source

Platforms as regulators

open access: yesJournal of Antitrust Enforcement, 2020
Abstract The proposition that certain digital platforms act as ‘regulators’ within their own business models is a key pillar of the European Commission report on Competition Policy for the Digital Era, and the basis upon which its authors build a wide-ranging duty for dominant platforms to secure competition that is ‘fair, unbiased and ...
openaire   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

CGIAR Excellence in Breeding Platform - Plan of Work and Budget 2021

open access: yes, 2021
The CGIAR Excellence in Breeding (EiB) Platform is accelerating the modernization of crop breeding programs that serve farmers in low- and middle-income countries.
CGIAR Excellence in Breeding Platform
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CGIAR Climate Impact Platform MELIA Framework

open access: yes
The theory of change (Annexed) outlines how the Climate Impact Platform contributes to global climate goals through five key impact pathways: 1)Research to Action: The platform leverages cutting-edge research to develop and apply climate adaptation and ...
CGIAR Climate Change Impact Platform
core   +1 more source

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