Results 191 to 200 of about 2,160,731 (244)

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto, Dariia Kliushnikova, Richard Friedrich Radlberger, Sinan Yasaroglu, Tobias Moser, Andrea Harrer, Kitty Kratzer, Wolfgang Hitzl, Christiane Gradl, Martin Schmidauer, Patrick Roth, Harald Hegen, Peter Wipfler   +12 more
wiley   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Platform economy & digital platforms

, 2020
openaire   +1 more source

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Addictive Platforms

Management Science, 2021
We study competition for consumer attention in which platforms can sacrifice service quality for attention. A platform can choose the “addictiveness” of its service. A more addictive platform yields consumers a lower utility of participation but a higher marginal utility of allocating attention.
Shota Ichihashi, Byung-Cheol Kim
openaire   +3 more sources

Platform Economy and Platformization

2020
In this book, we begin to interrogate the phenomenon of India’s expanding platform economy in terms of both rationale and process, linking a series of empirical inquiries to a critical analysis of the prevailing logics of ‘platform capitalism’ and ‘platformization’.
Athique, Adrian, Parthasarathi, Vibodh
openaire   +4 more sources

RACING THE PLATFORM/PLATFORMING RACE

AoIR Selected Papers of Internet Research, 2020
Race and racism are enduring structural forces that have a hand in virtually every aspect of society; the internet and its vast array of platforms, applications, devices, and cultures are well within their grasp (Nakamura and Chow-White, 2013; Brock, 2020).
Christopher Jahmail Persaud, Nick-Brie Guarriello, Elena Maris, Crystal Abidin, Meg Jing Zeng   +4 more
openaire   +1 more source

Divergent platforms [PDF]

Theory and Decision, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +5 more sources

ANRTS platforms

Proceedings of the 4th international workshop on Java technologies for real-time and embedded systems - JTRES '06, 2006
HIJA is an undertaking to create the technology conditions that will allow architecture neutrality for real-time systems (ANRTS). This paper makes the point that technology features are needed at both the execution level (platform) and the software engineering level (process).
Antonio Kung, Scott Hansen
openaire   +1 more source