Results 61 to 70 of about 181,614 (217)

Dendritic branching patterns in platforms of complex Ni-based single crystal castings [PDF]

open access: yesChina Foundry, 2019
Dendritic branching patterns at variable cross-sections in Ni-based single crystal (SX) castings of different generations were investigated using optical microscope (OM), electro probe microanalyzer (EPMA), differential scanning calorimeter (DSC ...
Min Huang1, *Gong Zhang1, Dong Wang1
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

RemoteLabs Platform

open access: yesInternational Journal of Online and Biomedical Engineering (iJOE), 2012
This paper reports on a first step towards the implementation of a framework for remote experimentation of electric machines â?? the RemoteLabs platform. This project was focused on the development of two main modules: the user Web-based and the electric machines interfaces.
Nils Crabeel   +2 more
openaire   +4 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Understanding of Digital Transformation and Its Background

open access: yesMaketingu Janaru, 2020
Recent evolutions in technology have enabled the rapid growth of digital companies through ecosystems, which have generated both threats and opportunities for existing companies who are struggling to adapt themselves to this rapidly changing environment.
Norio Imai
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The project “understAID” – a platform that helps informal caregivers to understand and aid their demented relatives

open access: yesJournal of Medical Science, 2014
“UnderstAID” is a platform that helps informal caregivers to understand and aid their demented relatives. It is an international project initiated by Denmark, Poland and Spain.
Elżbieta Skorupska   +5 more
doaj   +1 more source

The RECOVERY Platform

open access: yesNew England Journal of Medicine, 2021
The RECOVERY Platform Sharon-Lise Normand provides a biostatistician’s view of the preliminary findings on dexamethasone for Covid-19, noting that the results represent an important step and that t...
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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