Results 61 to 70 of about 3,889,089 (294)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
CGIAR GENDER Impact Platform Newsletter, April-May 2022, issue 1
, 2023 In this issue, we share with you latest news from the CGIAR GENDER Impact Platform as well as updates on gender research from across CGIAR's research portfolio.
CGIAR GENDER Impact Platform
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Journal of Business Economics and Management, 2019 With the embedding of internet technology, the entrepreneurial model has been gradually developing from traditional single linear channel into network platform with symbiotic multi-platform.
Jianlin Pan, Jie Lin
doaj +1 more source
A Study on Distribution and Characteristics of Radon Concentration in Metro Line 1 in Busan
대한환경공학회지, 2020 Objective:Adverse health effects of Radon with a particular focus on indoor environment has been outlined. Most of the metro stations and platforms are situated under the ground where relatively enhanced concentration of radon has been observed.
Seongwoo Choi +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A Survey of Deep Learning: Platforms, Applications and Emerging Research Trends
IEEE Access, 2018 Deep learning has exploded in the public consciousness, primarily as predictive and analytical products suffuse our world, in the form of numerous human-centered smart-world systems, including targeted advertisements, natural language assistants and ...
William Grant Hatcher, Wei Yu
doaj +1 more source
Dendritic branching patterns in platforms of complex Ni-based single crystal castings [PDF]
China Foundry, 2019 Dendritic branching patterns at variable cross-sections in Ni-based single crystal (SX) castings of different generations were investigated using optical microscope (OM), electro probe microanalyzer (EPMA), differential scanning calorimeter (DSC ...
Min Huang1, *Gong Zhang1, Dong Wang1
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source