Results 51 to 60 of about 5,361,118 (283)
A web-based platform for people with memory problems and their caregivers (CAREGIVERSPRO-MMD): Mixed-methods evaluation of usability [PDF]
, 2018 Background: The increasing number of people with dementia (PwD) drives research exploring Web-based support interventions to provide effective care for larger populations. In this concept, a Web-based platform (CAREGIVERSPRO-MMD, 620911) was designed to (
Antomarini, Marco +20 more
core +3 more sources
, 2020 The short story "Platform Socialism" is part of the anthology "twentyforty – Utopias for a Digital Society" that consisting out of visionary stories written by researchers, addressing the opportunities and challenges that digital technologies present for society in the future of 2040.
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Work platform is supported by self-locking blades [PDF]
, 1967 Work platform has a supporting plate to engage the deck edge of the supporting structure when lowered into place. The plate is attached to blades hinged to the platform, rigidly supporting the platform when latched, and allowing the platform to be moved ...
Rudderow, T.
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Study to gather evidence on the working conditions of platform workers VT/2018/032 Final Report 13 December 2019 [PDF]
, 2019 Platform work is a type of work using an online platform to intermediate between platform workers, who provide services, and paying clients. Platform work seems to be growing in size and importance.
De Groen, Willem Pieter +8 more
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Rotary leveling base platform [PDF]
, 1978 A leveling apparatus for the precise adjustment of a scientific instrument is reported. A base member is provided having a hollow cylindrical shape. A table for supporting the instrument rests on the base and has a shaft portion extending below the table.
Delaplaine, R. W., Mossolani, D. L.
core +1 more source