Results 71 to 80 of about 305,332 (304)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Service fabric: a distributed platform for building microservices in the cloud

open access: yesEuropean Conference on Computer Systems, 2018
We describe Service Fabric (SF), Microsoft's distributed platform for building, running, and maintaining microservice applications in the cloud. SF has been running in production for 10+ years, powering many critical services at Microsoft.
Gopal Kakivaya   +32 more
semanticscholar   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

CLOUD TECHNOLOGIES IN INNOVATIVE ACCOUNTING

open access: yesВестник Кемеровского государственного университета, 2013
Тhe research focuses on the innovations in accounting enabling to accumulate the resources of the organization more effectively, to reduce the costs associated with the acquisition of spare servers, etc.
R. T. Unshchikova, A. A. Ippolitowa
doaj  

Templet Web: the use of volunteer computing approach in PaaS-style cloud

open access: yesOpen Engineering, 2018
This article presents the Templet Web cloud service. The service is designed for high-performance scientific computing automation. The use of high-performance technology is specifically required by new fields of computational science such as data mining,
Vostokin Sergei   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

CYBER THREAT INTELLIGENCE AND INFORMATION SHARING IN CLOUD ECOSYSTEMS [PDF]

open access: yesProceedings on Engineering Sciences
The fast growth of cloud computing technologies has made CTI and information sharing inevitable and imperative to the improvement of cloud ecosystems' cybersecurity.
Ankur Mahida , Anuj Tyagi
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Crowdsourced Manufacturing in Industry 4.0: Implications and Prospects

open access: yesSystems
Crowdsourced manufacturing, which has emerged as a pivotal paradigm in the era of Industry 4.0, redefines traditional production models by leveraging decentralized decision-making and collaborative networks.
Xuejian Gong   +4 more
doaj   +1 more source

A Panorama of Cloud Platforms for IoT Applications Across Industries

open access: yesSensors, 2020
Internet of Things (IoT) applications can play a critical role in business and industry. Industrial IoT (IIoT) refers to the use of IoT technologies in manufacturing.
Sami Yangui
doaj   +1 more source

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