Results 21 to 30 of about 3,431,200 (298)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Developing Predictive Molecular Maps of Human Disease through Community-based Modeling [PDF]

open access: yes, 2011
The failure of biology to identify the molecular causes of disease has led to disappointment in the rate of development of new medicines. By combining the power of community-based modeling with broad access to large datasets on a platform that promotes ...
Christine Suver   +10 more
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Platform-Supported Cooperative Work

open access: yes, 2021
Platformization is transforming the way work is organized in a variety of businesses. The CSCW literature contains substantial amount of research on platforms, but this research to date has mainly been focusing on two-sided global platforms such as social media, on-demand labor, and crowdsourcing platforms.
Farshchian, Babak A.   +6 more
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Programming MPSoC platforms: Road works ahead! [PDF]

open access: yes2009 Design, Automation & Test in Europe Conference & Exhibition, 2009
This paper summarizes a special session on multicore/ multi-processor system-on-chip (MPSoC) programming challenges. The current trend towards MPSoC platforms in most computing domains does not only mean a radical change in computer architecture. Even more important from a SW developer´s viewpoint, at the same time the classical sequential von Neumann ...
Leupers, Rainer   +5 more
openaire   +2 more sources

A Ghost Workers' Bill of Rights: How to Establish a Fair and Safe Gig Work Platform [PDF]

open access: yes, 2020
Many of us assume that all the free editing and sorting of online content we ordinarily rely on is carried out by AI algorithms — not human persons. Yet in fact, that is often not the case.
Balkin, David   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Platform Work and the Danish Model – Legal Perspectives [PDF]

open access: yesNordic Journal of Commercial Law, 2018
Nordic Journal of Commercial Law, No 1 (2018)
Munkholm, Natalie Videbæk   +1 more
openaire   +4 more sources

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