Results 131 to 140 of about 241,602 (313)

Effect of distortion on the buckling strength of stiffened panels

, 2009
This paper predicts the behaviour of stiffened plates with different distortion levels in order to address a rational structural design procedure as pre-existing and fabricationrelated (like weld-induced) initial geometrical distortion is of great ...
Das, P.K., Hunt, Stuart, Crow, Anthony, Pretheesh, Paul C., Chaithanya, Pretheesh Paul, Das, Purnendu K.   +5 more
core   +1 more source

FRACCIONAMIENTO Y DESMETALIZACIÓN BIOCATALÍTICA DE ASFALTENOS DE CRUDO CASTILLA

CT&F Ciencia, Tecnología & Futuro, 1997
Se fraccionaron asfáltenos obtenidos a partir de crudo Castilla mediante cromatografía de adsorción en silica gel. Estos asfáltenos se caracterizaron parcialmente mediante cromatografía líquida de alta presión (HPLC), espectrofotometría UV-visible y ...
L. I MOGOLLÓN, R RODRÍGUEZ, W LARROTA, C ORTIZ, R TORRES   +4 more
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Wide-awake Local Anesthesia versus General Anesthesia for Clavicle Fracture Plating: A Retrospective Study

Formosan Journal of Musculoskeletal Disorders
Background: Plating of clavicle fracture has become a more favorable treatment option since it offers better functional outcome and less likelihood of malunion or nonunion.
Cheng-Yu Yin, Yi-Hung Chiang, Hui-Kuang Huang, I-Ning Lo, Yi-Chao Huang, Jung-Pan Wang   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Plating Wastewater Treatment

, 2017
Plating waste is potentially hazardous to human health and environment when they are not managed properly. The spent solvent, waste water, sludge and spent process solutions are the main waste pollutions which generated in large volumes daily in plating ...
Zhang, Yuzhe
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Personal Papers (MS 80-0002)

, 1948
Letter from Bronze-Art Casting & Plating Company to D. W.
Bronze-Art Casting & Plating Company, Dee, J.   +1 more
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source