Results 151 to 160 of about 40,453 (263)

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

open access: yesAdvanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano   +11 more
wiley   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

open access: yesAdvanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang   +4 more
wiley   +1 more source

Multicomponent Peptide‐MXene‐Hyaluronic Acid Hydrogel as a Conductive Scaffold for Enhanced Fibroblast Proliferation and Migration Under Electrical Stimulation

open access: yesAdvanced Healthcare Materials, EarlyView.
An electrically conductive FmocFF/MXene/hyaluronic acid hydrogel combines extracellular matrix‐like architecture, self‐healing behavior, oxidation‐resistant conductivity, and biochemical cues in a single scaffold. By enabling physiologically relevant electrical stimulation, the platform enhances fibroblast attachment, proliferation, and migration ...
Offir Loboda   +7 more
wiley   +1 more source

A platinum butterfly effect: small changes turn an anticancer drug into a non-toxic metalloantibiotic with in vivo efficacy. [PDF]

open access: yesNPJ Antimicrob Resist
Özsan Ç   +11 more
europepmc   +1 more source

Mechanically Compliant, Precision‐Porous Brain Implants Reduce the Foreign Body Reaction and Guide Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores how the brain responds to implants of different properties. Hydrogels with various mechanical properties and pore sizes were implanted in adult rat brains. It is observed that hydrogels with mechanical property closely matched to the brain and 40 µm pore size elicit a pro‐healing response from the brain by modulating the immune ...
Ian Dryg   +8 more
wiley   +1 more source

Elemental Stability in Mixed Noble and Non-Noble Metal High Entropy Alloy Nanoparticle Electrocatalysts. [PDF]

open access: yesChem Mater
Priamushko T   +5 more
europepmc   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

open access: yesAdvanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong   +12 more
wiley   +1 more source

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