Results 61 to 70 of about 1,492 (130)

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

Estuarine benthic diversity declines with temperature across a tropical–temperate gradient

Ecography, Volume 2026, Issue 10, October 2026.
Estuarine benthic sediments are important habitats that support ecosystem health and productivity, but the drivers of large‐scale patterns in benthic diversity are not well documented. Using 18S amplicon sequencing of 425 sediment DNA samples from estuaries spanning 20° of latitude along Australia's east coast, we assessed tropical–temperate patterns ...
Sally A. Bracewell, Mariana Mayer‐Pinto, Katherine A. Dafforn, Sebastian Vadillo Gonzalez, Thayanne L. Barros, Emma L. Johnston   +5 more
wiley   +1 more source

Kicking in the guts: Schistosoma mansoni digestive tract proteins are potential candidates for vaccine development

Frontiers in Immunology, 2015
Schistosomiasis is a debilitating disease that represents a major health problem in at least 74 tropical and subtropical countries. Current disease control strategies consist mainly of chemotherapy which cannot prevent recurrent re-infection of people ...
Barbara Castro-Pimentel Figueiredo, Barbara Castro-Pimentel Figueiredo, Natasha Delaqua Ricci, Natasha Delaqua Ricci, Natan Raimundo Gonçalves Assis, Natan Raimundo Gonçalves Assis, Suellen Batistoni Morais, Suellen Batistoni Morais, Cristina Toscano Fonseca, Cristina Toscano Fonseca, Sergio Costa Oliveira, Sergio Costa Oliveira   +11 more
doaj   +1 more source

Comprehensive Evaluation of Bisphenol A Toxicity Reveals Neurobehavioral, Metabolic, and Reproductive Impairments in Girardia tigrina

Environmental Toxicology, Volume 41, Issue 10, Page 849-861, October 2026.
ABSTRACT Bisphenol A (BPA), a common industrial chemical used in plastics and consumer products, is increasingly detected in aquatic environments, raising serious concerns about its potential ecological impacts. This study evaluated the sublethal and acute toxic effects of BPA on the freshwater planarian Girardia tigrina, a recognized model for ...
Raquel de Jesus Selestrino, Felipe Schaly, Welligton Luciano Braguini   +2 more
wiley   +1 more source

The Employment of Hydrogen Peroxide in Water Disinfection Poses a Threat to Aquatic Ecosystems Because of Its Toxicity to Nontarget Organisms

Environmental Toxicology, Volume 41, Issue 10, Page 1060-1068, October 2026.
ABSTRACT Hydrogen peroxide is widely used in water and wastewater treatment, particularly in advanced oxidation processes that aid in the degradation of compounds and microbial disinfection. Despite concerns about potential environmental contamination, its impact on freshwater ecosystems remains inadequately studied.
Letícia Queiroz Almeida, Thayrine Dias Carlos, Leydiane Barbosa Bezerra, Rone S. Barbosa, Nelson Luís Gonçalves Dias Souza, Douglas Henrique Pereira, Renato Almeida Sarmento, Grasiele Soares Cavallini   +7 more
wiley   +1 more source

Fossil constraints on the origin and evolution of Platyhelminthes are surprisingly concordant with modern molecular phylogenies [PDF]

Zoologia (Curitiba)
Trace fossils preserved with fossil worm-shaped remains suggest the presence of free-living flatworms during the Ordovician at the latest and their occurrence in terrestrial environments during the Permian.
Kenneth De Baets, Paula Dentzien-Dias, John Warren Huntley, Maarten P.M. Vanhove, Weronika Łaska, Aleksandra Skawina, Niels W.L. Van Steenkiste, Karina Vanadzina   +7 more
doaj   +1 more source

Aging Disrupts Tissue Homeostasis and Constrains Blastema‐Mediated Regeneration in the Cladonema Medusa

Aging Cell, Volume 25, Issue 10, October 2026.
Aging in Cladonema medusae disrupts tissue homeostasis and stem cell‐associated dynamics, accompanied by delayed wound closure and defective blastema formation. These age‐associated cellular changes culminate in incomplete functional tentacle regeneration, revealing how aging constrains regenerative capacity in a highly regenerative cnidarian ...
Ren Kanehisa, Hiroko Nakatani, Sho Takatori, Taisuke Tomita, Masayuki Miura, Yu‐ichiro Nakajima   +5 more
wiley   +1 more source

Assessing the occurrence of alien species on Brazilian freshwater ecosystems: insights from a comprehensive survey [PDF]

Acta Limnologica Brasiliensia
: Aim Assessing the damage caused to natural environments and native biodiversity by alien species is challenging. We tested whether the number of detections of alien species is affected by total alien or total invader alien species richness ...
Anderson Oliveira Latini, Daniela Chaves Resende, Daniel Paiva Silva, Dilermando Pereira Lima-Junior   +3 more
doaj   +1 more source

Functional insights into immunoglobulin superfamily proteins in invertebrate neurobiology and immunity

Frontiers in Immunology
The Immunoglobulin Superfamily (IgSF) represents a vital protein family widely distributed in animal genomes, encompassing multifunctional proteins with immunoglobulin-like domains, including immunoglobulins.
Hongyu Li, Hongyu Li, Yijie Zhang, Yunhuan Zhu, Qingzhi Zhao, Jialu Xu, Xianwei Li, Ling Zhao, Hairun Li, Mingcheng Liu, Yuncheng Qian, Xiaofen Zhang, Keda Chen   +12 more
doaj   +1 more source

Functional analysis of Girardia tigrina transcriptome seeds pipeline for anthelmintic target discovery

Parasites & Vectors, 2015
Background Neglected diseases caused by helminth infections impose a massive hindrance to progress in the developing world. While basic research on parasitic flatworms (platyhelminths) continues to expand, researchers have yet to broadly adopt a free ...
Nicolas J Wheeler, Prince N Agbedanu, Michael J Kimber, Paula Ribeiro, Tim A Day, Mostafa Zamanian   +5 more
doaj   +1 more source