Play therapy: A window into the child's world
Archives of Mental Health, 2011 Play therapy is a developmentally responsive modality uniquely suited for children to help prevent or resolve psychosocial difficulties and achieve optimal growth and development.
K J Vijay Sagar
doaj
Play Therapy As Effective Options for School-Age Children With Emotional and Behavioral Problems: A Case Series. [PDF]
Cureus, 2023 Gupta N +5 more
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Penatalaksaan Fisioterapi untuk Meningkatkan Kemampuan Visual pada Penderita Autism Spectrum Disorder (ASD) di Pusat Layanan Autis Sragen [PDF]
, 2018 Background : Autism Spectrum Disorder (ASD), also known as pervasive developmental disorder, is a group of delays and deviations in the development of social skills, language and communication, and behavior.
, Isnaini Herawati, S.Fis., M.Sc, +1 more
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Effectiveness of mandala coloring and playing with Lego on children’s preoperative anxiety: A Randomized Clinical Trial [PDF]
Journal of Research Development in Nursing and MidwiferyBackground: Mandala Coloring and Playing are distraction strategies to reduce the anxiety level in children. However, their effects are inconsistent and have received little attention for the management and prevention of anxiety in hospitalized children.
Azam Shirinabadi Farahani +5 more
doaj
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
The Effect of Cognitive-Behavioral Play Therapy on Improvements in Expressive Linguistic Disorders of Bilingual Children. [PDF]
Front Psychol, 2021 Rezaeerezvan S, Kareshki H, Pakdaman M.
europepmc +1 more source