Results 111 to 120 of about 603,031 (295)

P53/NANOG balance; the leading switch between poorly to well differentiated status in liver cancer cells

Frontiers in Oncology
Enforcing a well-differentiated state on cells requires tumor suppressor p53 activation as a key player in apoptosis induction and well differentiation.
Fazeleh Ranjbar-Niavol, Niloufar Rezaei, Ying Zhao, Hamed Mirzaei, Moustapha Hassan, Massoud Vosough, Massoud Vosough   +6 more
doaj   +1 more source

Player Pricing and Valuation of Cricketing Attributes: Exploring the IPL Twenty-Twenty Vision [PDF]

In April 2008, BCCI initiated Indian Premier League, a cricket tournament of Twenty-Twenty overs to be played among eight domestic teams. Team owners bid for the services of cricketers for a total of US$ 42 million.
Deodhar, Satish Y., Siddhartha K Rastogi
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Economic evaluation of football players through media value [PDF]

, 2016
This paper describes an approach based on media value to evaluate sport talent. We then apply this methodology to estimate the theoretical value of transfer fees for professional football players.
Garcia del Barrio, P., Pujol, F.
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Player and match characteristics associated with head acceleration events in elite-level men’s and women’s rugby union matches

BMJ Open Sport & Exercise Medicine
Objective To examine the likelihood of head acceleration events (HAEs) as a function of previously identified risk factors: match time, player status (starter or substitute) and pitch location in elite-level men’s and women’s rugby union matches.Methods ...
Keith A Stokes, Simon P T Kemp, Ben Jones, James Brown, Ross Tucker, Gregory Tierney, Lindsay Starling, Patrick O'Halloran, Matt Cross, David Allan, James Tooby, Éanna C Falvey, Danielle M Salmon, Sam Hudson   +13 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A Coase Theorem Based on a New Concept of the Core [PDF]

The core is reformulated to incorporate the externality typical in strategic form games. Any coalition of players may deviate by trying to commit to a profile of actions different from a status quo. The outsiders of the coalition may take a coordinated
Zheng, Charles Zhoucheng
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source