Results 271 to 280 of about 436,568 (329)

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

open access: yesVIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding   +10 more
wiley   +1 more source

Cellular signaling pathway of Shiga toxin-induced ATP release. [PDF]

open access: yesFront Cell Infect Microbiol
Johansson K   +4 more
europepmc   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

open access: yesVIEW, EarlyView.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li   +5 more
wiley   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li   +4 more
wiley   +1 more source

Fourteen‐analyser high‐resolution hard X‐ray emission spectrometer at I20 beamline at Diamond Light Source

open access: yesJournal of Synchrotron Radiation, EarlyView.
A high‐efficiency 14‐analyser X‐ray emission spectrometer that offers novel capabilities has been developed for I20‐Scanning at Diamond Light Source.We report the technical design, implementation and operation of a newly developed X‐ray emission spectrometer on the I20 beamline at Diamond Light Source.
Shusaku Hayama   +8 more
wiley   +1 more source

Peripheral lymphocyte count as a prognostic marker in cervical cancer patients treated with immune checkpoint inhibitors: a retrospective study. [PDF]

open access: yesBMC Cancer
Dofutsu M   +10 more
europepmc   +1 more source

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