Results 151 to 160 of about 23,583 (245)

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, Volume 111, Issue 3, Page 653-673, 1 March 2026.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source

Ventilatory Complexity Persists in Phox2b Mutant Mice Lacking the Retrotrapezoid Nucleus/Parafacial Respiratory Group (RTN/pFRG) and in Humans With Congenital Central Hypoventilation Syndrome. [PDF]

J Comp Neurol
Straus C, Ranohavimparany A, Ramanantsoa N, Tremoureux L, Patout M, Fiamma MN, Cayetanot F, Matrot B, Gallego J, Bodineau L, Similowski T.   +10 more
europepmc   +1 more source

The hypoxic ventilatory response and arousal burden predict the magnitude of ventilatory long‐term facilitation in humans with obstructive sleep apnoea

Experimental Physiology, Volume 111, Issue 3, Page 1441-1453, 1 March 2026.
Abstract The magnitude of progressive augmentation (PA) and ventilatory long‐term facilitation (vLTF) are two forms of respiratory plasticity that are enhanced in some humans with obstructive sleep apnoea (OSA). This response might be linked to repeated nocturnal exposure to intermittent hypoxia or other traits connected to OSA.
Jason H. Mateika, Danny Hammo, Dylan M. Kissane, Ali Azarbarzin   +3 more
wiley   +1 more source

Perioperative micro-arterial function and extravasation in cytoreductive ovarian cancer surgery: an observational study. [PDF]

Intensive Care Med Exp
Feldheiser A, Dathe JJ, Heinig S, Pietzner K, Kaufner L, Hunsicker O, von Haefen C, Sehouli J, Spies C.   +8 more
europepmc   +1 more source

A new method for bedside determination of effective lung volume and functional residual capacity

Experimental Physiology, Volume 111, Issue 3, Page 620-624, 1 March 2026.
Abstract Established methods of measuring functional residual capacity (FRC) involve sophisticated equipment and elaborate procedures. Here we present a new method based on CO2 rebreathing that has a simple fast procedure and only requires end‐tidal CO2 monitoring. Ten healthy subjects with diverse anthropometric and respiratory parameters were studied
Andras Gedeon, Jakob Jansson, David Patrickson, Mats Wallin   +3 more
wiley   +1 more source

Differences in severity grading of lung hyperinflation using GLI <i>versus</i> ECSC reference values. [PDF]

ERJ Open Res
Wahab L, Windisch W, Criée CP, Dreher M, Cornelissen CG.   +4 more
europepmc   +1 more source

Oral amino acid tracer delivery detects feeding and exercise changes in myofibrillar protein synthesis rates in male adults

Physiological Reports, Volume 14, Issue 5, March 2026.
Male participants were randomly assigned to consume [13C]leucine and [D5]phenylalanine tracers alone (FAST) or with a complete mixture of amino acids (0.25 g/kg) and carbohydrate (0.75 g/kg) at rest (FED) or after a bout of resistance exercise (EXFED). Plasma enrichment of both tracers increased rapidly after ingestion and remained elevated for up to 4–
Michael Mazzulla, Nathan Hodson, Paula J. Scaife, Kenneth Smith, Philip J. Atherton, Nicholas A. Burd, Dinesh A. Kumbhare, Daniel R. Moore   +7 more
wiley   +1 more source

Whole lung directed anti-muscarinic therapy improves small airway dysfunction in COPD patients. [PDF]

Eur Respir J
Usmani OS, Toumpanakis D, Meah S, Mak V, Biddiscombe MF.   +4 more
europepmc   +1 more source

Cardiovascular effects of exercise training in spontaneously hypertensive rats: A systematic review and meta‐analysis

Physiological Reports, Volume 14, Issue 5, March 2026.
Abstract Exercise is recommended as a nonpharmacological intervention to lower blood pressure in individuals with hypertension, yet optimal exercise parameters and physiological factors influencing its effectiveness remain incompletely understood. We conducted a meta‐analysis to quantify the effects of treadmill‐based exercise training in spontaneously
Stephen W. Luckey, Rohan Sethi, Natalie S. Crouse, Kayla M. Meredith, Rachael Bush   +4 more
wiley   +1 more source