Results 151 to 160 of about 31,642 (278)

Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis

British Journal of Pharmacology, Volume 183, Issue 16, Page 4592-4609, August 2026.
Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu, Zengbing Lu, Julia Yuen Hang Liu, Man Piu Ngan, Kai‐Hei Tse, John Anthony Rudd   +5 more
wiley   +1 more source

Effects of Calorie Restriction With and Without Strength, Endurance or Mixed Training on Fat‐Free and Skeletal Muscle Mass in Overweight or Obese Individuals—A Systematic Review With Pairwise Meta‐Analysis and Network Meta‐Analysis of Randomized Controlled Studies

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6810-6823, August 2026.
ABSTRACT Aims Calorie restriction (CR) reduces both fat mass and fat‐free mass (FFM), particularly skeletal muscle mass (SMM), which is essential for cardiometabolic health and preventing frailty. This study compares CR alone versus CR plus exercise (EX) on FFM and SMM in overweight/obese patients and examines the effects of different training modes ...
Magdalena Deller, Jan Weiershaus, Steffen Held, Christian Brinkmann   +3 more
wiley   +1 more source

The role of strain gauge plethysmography in the assessment of patients with suspected deep vein thrombosis [PDF]

Suspicion of deep vein thrombosis (DVT) is a common reason for medical referral to hospital. Clinical signs and symptoms are notoriously unreliable, hence there is the need for objective testing.
Robinson BJ, Kesteven PJL, Elliott ST
core  

Nocturnal Sleep Breathing Patterns in Healthy Adolescents Residing at Very High Altitudes in Bolivia

Journal of Sleep Research, Volume 35, Issue 4, August 2026.
ABSTRACT Data on sleep and respiratory patterns among adolescents residing at very high altitude (> 3500 m) remain scarce, and altitude‐related physiological differences may influence these parameters. Studying adolescents at different very high altitudes is crucial, as subtle environmental variations could affect sleep‐related oxygenation and ...
Keaton Patterson, Santiago Ucrós Rodríguez, E. Nicolás Arancibia‐Levit, Fernanda Aliaga Raduan, José Antonio Viruez Soto, Max Gassmann, Silvia Ulrich, Michael Furian, Edith M. Schneider Gasser   +8 more
wiley   +1 more source

Validation of respiratory inductance plethysmography ("Respitrace") for the measurement of tidal breathing parameters in newborns. [PDF]

, 1992
Validation of respiratory inductance plethysmography ("Respitrace") for the measurement of tidal breathing parameters in ...
SM Stick (14457273), E Ellis (7729136), PN LeSouëf (14458896), PD Sly (14453628)   +3 more
core  

Sleep Disordered Breathing Severity Alters Overnight Temperature Changes in Children

Journal of Sleep Research, Volume 35, Issue 4, August 2026.
ABSTRACT The quality of sleep is very closely related to variations in body temperature. We aimed to assess the feasibility of skin temperature measurements in children attending the sleep laboratory for routine polysomnography and to determine whether there was a difference in body temperature between children with different severities of sleep ...
Georgina Plunkett, Marisha Shetty, Maria Vaz‐Serra, Stephane Delanaud, Lauren C. Nisbet, Margot J. Davey, Gillian M. Nixon, Rosemary S. C. Horne, Veronique Bach   +8 more
wiley   +1 more source

A gradual and sustainable approach to diagnosing sleep and circadian disturbances in dementia

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract Evidence linking sleep and circadian disruptions to the course of dementias, particularly Alzheimer's disease, has expanded. Such alterations are detectable from preclinical stages and parallel the disease progression. Assessing and managing sleep and circadian disturbances in patients with dementia remains challenging.
Biancamaria Guarnieri, Domeniko Hoxhaj, Francesca Buracchi Torresi, Dario Arnaldi, Enrica Bonanni, Matteo Carpi, Riccardo Cremascoli, Claudio Liguori, Gemma Lombardi, Greta Mainieri, Federica Provini, Rosalia Silvestri, Monica Puligheddu, Michelangelo Maestri Tassoni   +13 more
wiley   +1 more source

Sympathetic Overactivation Drives Neurogenic Alveolar Epithelial Pyroptosis via the PIEZO2‐ER Stress Pathway in Acute Lung Injury Following Intracerebral Hemorrhage

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Following intracerebral hemorrhage, sympathetic overactivation drives acute lung injury via norepinephrine‐induced VPS35 upregulation. VPS35 promotes PIEZO2‐mediated calcium influx and impairs ATP2A2‐dependent ER calcium reuptake, triggering ER stress and NLRP3‐pyroptosis.
Shuai Han, Zirui Wang, Qiuyue Zheng, Feng Guo, Yinggang Xiao, Zi Wang, Tianfeng Huang, Yongxin Liang, Bingchun Yan, Ju Gao   +9 more
wiley   +1 more source

Tissue and Serum Concentrations of Time‐Dependent Antibiotics in Infected Diabetic Foot Ulcers by Bolus or Continuous Administration: The Randomised DFIATIM Trial

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 5, July 2026.
ABSTRACT Aims The clinical effectiveness of antibiotic (ATB) therapy in patients with infected diabetic foot ulcers (iDFUs) depends on achieving sufficient ATB concentrations in both serum and peripheral tissues. This study evaluated the availability and bactericidal activity of the time‐dependent ATBs—ceftazidime (CTZ) and amoxicillin/clavulanate (AMC)
Radka Jarošíková, Dominika Sojáková, Simona Antalová, Petr Tůma, Jan Polák, Michal Dubský, Andrea Němcová, Veronika Wosková, Pavol Beca, Istvan Modos, Jan Mareš, Jakub Mrázek, Chahrazed Mekadim, Markéta Skružná, Vladimíra Fejfarová   +14 more
wiley   +1 more source

The Effects of Glucagon‐Like Peptide‐1 Receptor Agonists and Sodium‐Glucose Co‐Transporter‐2 Inhibitors on Lean Body Mass in Humans: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 5, July 2026.
ABSTRACT Aims The use of pharmacotherapies with weight loss properties for the management of obesity and chronic disease are now routinely prescribed. We investigated the evidence from randomised‐controlled trials for the effects on lean body mass of glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) and sodium‐glucose co‐transporter‐2 inhibitors ...
Rishi Jobanputra, Jack A. Sargeant, Tatiana Plekhanova, Emily James, Abdullah Almaqhawi, David R. Webb, Melanie J. Davies, Thomas Yates   +7 more
wiley   +1 more source