Results 51 to 60 of about 84,093 (308)
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Bilateral Presentation of Pleural Desmoplastic Small Round Cell Tumors: A Case Report
대한영상의학회지, 2015 Desmoplastic small round cell tumor (DSRCT) is a highly aggressive malignant small cell neoplasm occurring mainly in the abdominal cavity, but it is extremely rare in the pleura.
You Sun Won +6 more
doaj +1 more source
Primary Leiomyoma of the pleura [PDF]
, 2011 Primary leiomyoma of the pleura is extremely rare. A 45-year-old man presented with a complaint of right chest pain. Chest computed tomography demonstrated a solid, round pleural mass in the right anterior chest wall.
Daxin Zhu +5 more
core +1 more source
Advanced Science, EarlyView.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Advanced Science, EarlyView.We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang +11 more
wiley +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Extraskeletal mesenchymal chondrosarcoma of the pleura: Report of a rare case
Indian Journal of Pathology and Microbiology, 2011 Mesenchymal chondrosarcoma is a rare aggressive variant of chondrosarcoma that frequently occurs in extraskeletal location. A 28-year-old female presented with a history of dyspnea and fever and succumbed to her illness before a conclusive diagnosis was ...
Ayushi Jain +3 more
doaj +1 more source
KADAR INTERFERON GAMMA (IFN-γ) CAIRAN PLEURA PADA EFUSI PLEURA TUBERKULOSIS DAN NON-TUBERKULOSIS [PDF]
, 2016 Kadar IFN-γ Cairan Pleura pada Efusi Pleura TB dan Non-TB ABSTRAK Latar Belakang: Diagnosis efusi pleura TB sampai saat ini masih jadi permasalahan, karena tingkat kepositifan M.Tb pada efusi pleura TB rendah pada beberapa pemeriksaan seperti ...
FAHMI NOFRIANDI, FAHMI
core
Representative figures for hemi-split pleura sign (A, B) and split pleura sign (C, D).
, 2015 Thickened visceral or parietal pleura on thoracic CT show the “hemi-split pleura sign” (A, B). When both pleura are thickened and separated by effusion, this is defined as the “split pleura sign” (C, D).
Richard W. Light (755079) +9 more
core +1 more source
Consumed by Abdominal Distention
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge +3 more
wiley +1 more source