Results 181 to 190 of about 262,263 (283)

Clinical Outcomes of Different Generation EGFR TKIs in Susceptible EGFR‐Mutated Advanced Nonsmall‐Cell Lung Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are indicated for advanced lung adenocarcinoma patients harboring susceptible EGFR mutations. The aim of this retrospective study was to compare the effectiveness of different generations of EGFR TKIs.
Chia‐Yu Kuo, Tien‐Chi Huang, Chih‐Jen Yang, Mei‐Hsuan Lee, Jui‐Ying Lee, Ying‐Ming Tsai, Kuan‐Li Wu, Cheng‐Hao Chuang, Inn‐Wen Chong, Jen‐Yu Hung   +9 more
wiley   +1 more source

A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti-PD-1 Agent Pembrolizumab. [PDF]

Cancer Discov, 2021
Adusumilli PS, Zauderer MG, Rivière I, Solomon SB, Rusch VW, O'Cearbhaill RE, Zhu A, Cheema W, Chintala NK, Halton E, Pineda J, Perez-Johnston R, Tan KS, Daly B, Araujo Filho JA, Ngai D, McGee E, Vincent A, Diamonte C, Sauter JL, Modi S, Sikder D, Senechal B, Wang X, Travis WD, Gönen M, Rudin CM, Brentjens RJ, Jones DR, Sadelain M.   +29 more
europepmc   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Unraveling the mystery of pleural calcifications: a diagnostic challenge in pleural disease. [PDF]

Arch Med Sci Atheroscler Dis
Leivaditis V, Mulita F, Liolis E, Nikolakopoulos K, Tasios K, Litsas D, Krinos N, Antzoulas A, Tchabashvili L, Grapatsas K, Koletsis E, Papadoulas S, Dahm M.   +12 more
europepmc   +1 more source

Recent Advancements in the Characterization of D‐Amino Acid and Isoaspartate Post‐Translational Modifications

Mass Spectrometry Reviews, EarlyView.
ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley   +1 more source

Pleural Effusion: Shedding Light on Pleural Disease Beyond Infection and Malignancy. [PDF]

Medicina (Kaunas)
Harding WC, Halawa AR, Aiche MM, Zafar B, Ali HR, Bashoura L, Faiz SA.   +6 more
europepmc   +1 more source

Intrapleural interleukin-2-expressing oncolytic virotherapy enhances acute antitumor effects and T-cell receptor diversity in malignant pleural disease. [PDF]

J Thorac Cardiovasc Surg, 2022
Ekeke CN, Russell KL, Murthy P, Guo ZS, Soloff AC, Weber D, Pan W, Lotze MT, Dhupar R.   +8 more
europepmc   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Melanoma of the pleura mimicking malignant mesothelioma: a rare and rapidly progressive pleural disease. [PDF]

BMJ Case Rep
Edland B, Stanley C, Yap FHX, Weerakkody Y.   +3 more
europepmc   +1 more source

Thoracic ultrasound in the modern management of pleural disease. [PDF]

Eur Respir Rev, 2020
Hassan M, Mercer RM, Rahman NM.
europepmc   +1 more source