Results 21 to 30 of about 4,888,020 (205)

Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study. [PDF]

, 2011
BACKGROUND: The effects of extra-pleural pneumonectomy (EPP) on survival and quality of life in patients with malignant pleural mesothelioma have, to our knowledge, not been assessed in a randomised trial.
Kilburn, L.S., Senan, S., Spicer, J., Coombes, G., Loic Lang-Lazdunski, O'Brien, M., Lang-Lazdunski, Loic, Treasure, T., Peto, Julian, Edwards, John, Michael Snee, Landau, David, David Waller, O'Byrne, Ken, Thomas, G., MARS trialists, O'Byrne, Kenneth J., Bliss, J.M., Landau, D., Tan, Carol, ?, ?, Entwisle, J., Liz Darlison, Kilburn, Lucy S, Edwards, J., Snee, M., Mary O'Brien, Peto, J., Waller, D., Spicer, James; id_orcid, Waller, David, Darlison, Liz, Gill Coombes, Darlison, L., Judith M Bliss, Suresh Senan, James Entwisle, Kilburn, Lucy S., Ken O'Byrne, Carol Tan, Bliss, Judith M., Treasure, Tom, O'Byrne, K., Snee, Michael, O'Brien, Mary, Lucy S Kilburn, Tom Treasure, Bliss, Judith M, Entwisle, James, John Edwards, David Landau, Senan, Suresh, James Spicer, Coombes, Gill, Tan, C., Gill Thomas, Spicer, James, Lang-Lazdunski, L., Julian Peto, Thomas, Gill   +59 more
core   +1 more source

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

Cancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada, Mitsuhiro Isaka, Akira Ono, Takuya Kawata, Masakuni Serizawa, Keita Mori, Koji Muramatsu, Kiyoshi Tone, Hirotsugu Kenmotsu, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Yasuto Akiyama, Takashi Sugino, Toshiaki Takahashi, Yasuhisa Ohde   +16 more
wiley   +1 more source

Pleural cryobiopsy is useful for comprehensive cancer genetic panel testing

Respirology Case Reports, 2020
An 83‐year‐old woman presented with dyspnoea. Her chest X‐ray showed a right‐sided pleural effusion. Flex‐rigid pleuroscopy was performed and showed a mass in the anterior portion.
Satoru Ishii, Hiromu Watanabe, Shinyu Izumi, Masayuki Hojo, Haruhito Sugiyama   +4 more
doaj   +1 more source

Case Report: Indwelling Pleural Catheter Based Management of Refractory Hepatic Hydrothorax as a Bridge to Liver Transplantation

Frontiers in Medicine, 2021
Introduction: Liver transplantation is the treatment of choice for decompensated liver disease, and by extension for hepatic hydrothorax. Persistent pleural effusions make it challenging for patients to maintain physiological fitness for transplantation.
Mayurun Selvan, Hannah Collins, William Griffiths, William Gelson, Jurgen Herre   +4 more
doaj   +1 more source

Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]

, 2010
The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J, Landwehrmeyer, G Bernhard, Aileen K Ho, Bisson, Jonathan Ian, Schwenke C, David Craufurd, Dunnett, Stephen B., Handley, Olivia, Investigators of the European Huntington's Disease Network, The, DI MARIA, EMILIO, Craufurd D, Dunnett, SB, Carsten Schwenke, the investigators of the European Huntington's Disease Network, Craufurd, David, Edward Wild, Landwehrmeyer, GB, Busse, Monica, Rosser, Anne Elizabeth, Olivia J Handley, Romano Silvia., Tabrizi SJ, Ho, Aileen K., Wild, E, Landwehrmeyer GB, Craufurd, D, Tabrizi, SJ, Tabrizi, Sarah J., Handley, OJ, Rickards, Hugh, Dunnett, Stephen, Ho, Aileen K, Orth, Michael, Ho, AK, Wild, Edward, Stephen B. Dunnett, Sarah J Tabrizi, Wild, EJ, Landwehrmeyer, G. Bernhard, Naji, Jenny, Landwehrmeyer, G. Bernhard, Wild E, Investigators of the European Huntington's Disease Network, Handley, Olivia J., Orth, M, Ellison-Rose, Lynda, Tabrizi, Sarah J, Price, Kathleen, Ho AK, ABBRUZZESE, GIOVANNI, Schwenke, C, Ho, A, Orth M, Handley OJ, Schwenke, Carsten, Dunnett SB, Dunnett, Stephen B, Michael Orth, G. Bernhard Landwehrmeyer   +59 more
core   +1 more source

Health‐related quality of life following total minimally invasive, hybrid minimally invasive or open oesophagectomy: a population‐based cohort study

BJS (British Journal of Surgery), EarlyView., 2020
All patients operated for oesophageal cancer in Sweden from 2013 to April 2018 were identified, and 246 patients were recruited to this population‐based nationwide Swedish study. The results show that longitudinal health‐related quality of life after minimally invasive oesophagectomy was similar to that of the open surgical approach.
F. Klevebro, J. H. Kauppila, S. Markar, A. Johar, P. Lagergren   +4 more
wiley   +1 more source

The prevalence and prognostic significance of Sarcopenia and Adipopenia in Pleural Mesothelioma

Cancer Treatment and Research Communications
Introduction: Altered body composition is associated with adverse survival in multiple cancers. We determined the prevalence, prognostic significance and clinicopathological correlates of sarcopenia and adipopenia in Pleural Mesothelioma (PM) patients ...
Andrew C. Kidd, Gordon W. Cowell, Geoffrey A. Martin, Jenny Ferguson, Dean A. Fennell, Matt Evison, Kevin G. Blyth   +6 more
doaj   +1 more source

Pneumothorax: An update on clinical spectrum, diagnosis and management

Clinical Medicine
Pneumothorax is defined as air in the pleural space and is characterised by chest pain and breathlessness. It is commonly divided into spontaneous and non-spontaneous subtypes based on the underlying mechanism.
Beenish Iqbal, Rob Hallifax, Najib M. Rahman   +2 more
doaj   +1 more source

Clinical Significance of Pleural Lactate Measurement in Critically Ill Patients with Parapneumonic Pleural Effusion

, 2023
OBJECTIVE: Pleural fluid pH measurement is recommended for tube thoracostomy decisions in complicated parapneumonic pleural effusions. However, pleural fluid pH may be affected by blood pH in critically ill patients with common systemic acid-base ...
Mehmet Nuri Yakar, KÜÇÜK, MURAT, Ali Necati Gokmen, Volkan Hancı, Mehmet Celal Ozturk, Ahmet Naci Emecen, Begum Ergan, Murat Kucuk, Emecen, AHMET NACİ, ERGÜN, BİŞAR, Volkan Hanci, HANCI, VOLKAN, GÖKMEN, ALİ NECATİ, CÖMERT, BİLGİN, Vecihe Bayrak, Bilgin Comert, ERGAN, BEGÜM, Bisar Ergun, YAKAR, MEHMET NURİ, ÖZTÜRK, MEHMET CELAL, BAYRAK, VECİHE   +20 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source