Results 41 to 50 of about 118,850 (258)

Pleural effusion in sarcoidosis patients

open access: yesТуберкулез и болезни лёгких, 2020
The article presents the review of 62 publications which demonstrated that 1.1-16.7% of patients with pulmonary sarcoidosis develop plural effusion.
N. A. Stogova
doaj   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

open access: yesAdvanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima   +15 more
wiley   +1 more source

CT in differential diagnosis of benign and malignant pleural disease

open access: yesMonaldi Archives for Chest Disease, 2005
Background. CT plays a valuable role in assessment of patients with a wide variety of diseases of the pleura, and pulmonologists should be aware of the significance of different CT findings for the differential diagnosis of benign and malignant pleural ...
U. Yilmaz   +4 more
doaj   +1 more source

Epidemiologic evaluation of pleurisy diagnosed by surgical pleural biopsy using data from a nationwide administrative database

open access: yesThoracic Cancer, 2022
Background Pleural biopsies for investigating the causes of pleurisy are performed through modalities including needle biopsies, local anesthetic thoracoscopic procedures, and surgery (video‐assisted thoracoscopic surgery and open thoracotomy).
Kanako Hara   +10 more
doaj   +1 more source

Ultrathin Hydrogel Membranes Inspired by Soap Films Enable Physiologically Relevant Breathing Lung Models

open access: yesAdvanced Materials, EarlyView.
A soap‐film inspired strategy enables the fabrication of ultrathin yet robust GelMA‐PAAm membranes for breathing lung culture. The hydrogel membrane supports long‐term cyclic deformation under air‐liquid interface conditions, enabling physiologically relevant breathing motions of engineered lung tissue culture. ABSTRACT Breathing continuously stretches
Yunji Lee   +9 more
wiley   +1 more source

Investigating Partial Registration for Optimizing Robotic-Assisted Bronchoscopy Evaluations of Peripheral Lung Nodules (I-PROBE)Take-Home Points

open access: yesCHEST Pulmonary
Background: Robotic-assisted bronchoscopy has transformed the diagnostic approach to lung cancer by improving access to peripheral pulmonary lesions (PPLs). Among these platforms, shape-sensing robotic-assisted bronchoscopy (ssRAB) relies on registration
Bryce Duchman, MD   +8 more
doaj   +1 more source

Video‐assisted surgical diagnosis and pleural adhesion management in catamenial pneumothorax: A case and literature review

open access: yesRespirology Case Reports, 2023
Catamenial pneumothorax is a rare primary spontaneous pneumothorax associated with the menstrual phase and is the most common manifestation of thoracic endometriosis syndrome.
Irandi Putra Pratomo   +8 more
doaj   +1 more source

Stromal‐Derived IL‐8 Promotes M2 Macrophage Polarization via the RhoA/MRTF‐A/SRF Transcriptional Axis to Impair CD8+ T Cell Cytotoxicity in Lung Cancer

open access: yesAdvanced Science, EarlyView.
In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu   +7 more
wiley   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

open access: yesAdvanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu   +17 more
wiley   +1 more source

Non-invasive prediction of non-tuberculous benign pleural effusion: can we avoid unnecessary pleural biopsies?

open access: yesBMC Pulmonary Medicine
Background Accurate differentiation between malignant and benign pleural effusions remains a diagnostic challenge, often requiring invasive procedures. This study aims to identify predictive markers and develop a model based on clinical, laboratory, and ...
Muzaffer Metintas   +7 more
doaj   +1 more source

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