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Phenotyping malignant pleural effusions
Current Opinion in Pulmonary Medicine, 2016Patients with malignant pleural effusions (MPEs) are heterogenous in their disease course, symptom severity, responses to cancer therapies, fluid recurrence rates, and thus need for definitive fluid control measures. To tailor the most appropriate treatment for individual patients, clinicians need to 'phenotype' the patients and predict their clinical ...
Macy M S, Lui +2 more
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Pleural Effusion from Malignancy
Annals of Internal Medicine, 1978Pleural effusion from metastatic malignancy can cause major impairment of respiratory function and eventual death. Although cure is not possible, successful palliative treatment allows months to years of productive life, obviating the need for continuous hospitalization and repeated thoracenteses.
A, Leff, P C, Hopewell, J, Costello
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Current Treatment Options in Oncology, 2001
Malignant pleural effusions contribute to considerable morbidity in cancer patients and generally portend an overall poor prognosis. Treatment of malignant pleural effusions is palliative; therefore, quality of life issues, as well as the risks and benefits of the therapeutic options, become more critical.
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Malignant pleural effusions contribute to considerable morbidity in cancer patients and generally portend an overall poor prognosis. Treatment of malignant pleural effusions is palliative; therefore, quality of life issues, as well as the risks and benefits of the therapeutic options, become more critical.
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Postgraduate Medicine, 1986
Pleural effusions are common in cancer patients, developing either from the malignant condition or from unrelated causes, such as congestive heart failure, pulmonary infarction, or infection. Diagnosis of malignant pleural effusion rests on demonstration of the presence of malignant cells in the pleural fluid or pleural biopsy specimen.
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Pleural effusions are common in cancer patients, developing either from the malignant condition or from unrelated causes, such as congestive heart failure, pulmonary infarction, or infection. Diagnosis of malignant pleural effusion rests on demonstration of the presence of malignant cells in the pleural fluid or pleural biopsy specimen.
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2004
The presence of pleural effusions is a common clinical problem in patients with neoplastic disease. At the time of diagnosis, approximately 15% of lung cancer patients have a pleural effusion (Naito et al. 1997).Twenty to 50% of patients with advanced or disseminated lung cancer develop a pleural effusion during the course of the ir disease (Emerson et
van Schil, Paul, Germonpré, Paul
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The presence of pleural effusions is a common clinical problem in patients with neoplastic disease. At the time of diagnosis, approximately 15% of lung cancer patients have a pleural effusion (Naito et al. 1997).Twenty to 50% of patients with advanced or disseminated lung cancer develop a pleural effusion during the course of the ir disease (Emerson et
van Schil, Paul, Germonpré, Paul
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Management of Malignant Pleural Effusions
Drugs, 1998Malignant pleural effusions (MPEs) represent a common complication of advanced malignancies. However, adequate palliation of this highly symptomatic accompaniment to cancer can be achieved in most patients by adopting the appropriate therapy. Several options are available for the treatment of MPE.
Grossi F +4 more
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Surgical Clinics of North America, 2002
The management of pleural effusions and, in particular, recurrent MPE require an accurate assessment of the characteristics of the pleural fluid and the relief of the patient's symptoms. Although a common problem, treatment of pleural effusions and MPE is highly variable.
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The management of pleural effusions and, in particular, recurrent MPE require an accurate assessment of the characteristics of the pleural fluid and the relief of the patient's symptoms. Although a common problem, treatment of pleural effusions and MPE is highly variable.
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Annals of Internal Medicine, 1978
Excerpt To the editor: To the excellent review of malignant pleural effusion by Leff, Hopewell, and Costello (Ann Intern Med88:532-537, 1978) I wish to add these practical clinical points. 1.
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Excerpt To the editor: To the excellent review of malignant pleural effusion by Leff, Hopewell, and Costello (Ann Intern Med88:532-537, 1978) I wish to add these practical clinical points. 1.
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Recurrent Malignant Pleural Effusions
New England Journal of Medicine, 1964IT is the unfortunate lot of some patients dying of metastatic cancer of the breast, lung, cervix and so forth to be plagued by severe dyspnea due to recurrent malignant pleural effusions. Many of these people would have several months of relative comfort at home if they could only breathe.
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Management of Malignant Pleural Effusions
Chest, 1993Malignant pleural effusions (MPEs) are a common complication of advanced malignancies, particularly lung and breast cancer. They are caused by a variety of mechanisms including tumor obstruction of lymphatic flow, spread of malignant cells via the systemic circulation, and tumor invasion of the pulmonary arterioles.
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