Results 41 to 50 of about 104,742 (284)

Diagnostic value of calprotectin in differentiation between benign and malignant pleural effusion

The Egyptian Journal of Bronchology, 2019
Background Pleural effusion can arise as a result of more than 50 recognized causes and the differentiation between benign and malignant origin of the fluid is still a diagnostic challenge.
Omar M. Mohammed, Kamel M. Hussein, Abdelgawad E. Ramadan, Gouda T. Mahmoud, Marwa El-Sayed El-Naggar, Nor Eldein Z. Gaber   +5 more
doaj   +1 more source

Clinical Value of Pleural Effusion and Serum MMP-3 and CYFRA21-1 Combined with ADA in Differential Diagnosis of Pleural Exudative Effusion

Emergency Medicine International, 2022
Objective. The aim of the study is to investigate the clinical value of matrix metalloproteinases-3 (MMP-3) and cytokeratin 19 fragment antigen 21-1 (CYFRA21-1) combined with adenosine deaminase (ADA) in pleural effusion and serum in benign and malignant
Zhiyang Xu, Jun Guan, Jianxin Xu, Jiahua Tu, Jiangdong Cheng   +4 more
doaj   +1 more source

Contemporary approach to the patient with malignant pleural effusion complicating lung cancer.

Annals of Translational Medicine, 2019
Malignant pleural effusion (MPE) occurring in the patient with lung cancer can have profound prognostic and management implications. If clinically relevant, such an effusion first needs to be confirmed as malignant and then, in the majority of lung ...
O. Epelbaum, N. Rahman
semanticscholar   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Exosomal MicroRNA Expression Profiling in Patients with Lung Adenocarcinoma-associated Malignant Pleural Effusion

Anticancer Research, 2018
Background/Aim: Cytological analysis for diagnosing malignant pleural effusion associated with lung adenocarcinoma (Ad-MPE) shows limited sensitivity and novel diagnostic biomarkers are needed.
H. Tamiya, A. Mitani, Akira Saito, Taro Ishimori, Minako Saito, Hideaki Isago, T. Jo, Y. Yamauchi, G. Tanaka, T. Nagase   +9 more
semanticscholar   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

A novel interleukin 36 gamma for diagnosing and differentiating malignant from infectious pleural effusion

Egyptian Journal of Chest Disease and Tuberculosis
Background Pleural effusions can be caused by various diseases, making their diagnosis challenging. Light’s criteria are often used to distinguish transudative and exudative effusions.
Nashwa A. Amin, Asmaa E. Mohamed, , Shimaa M.E. Wahdan, Amira E. Ramadan, Shimaa M. Mohammed, Marwa S.E. Abd-Elraouf, Kout A.M. Diab   +6 more
doaj   +1 more source

Diagnostic significance of pleural fluid pH and pCO2

Egyptian Journal of Chest Disease and Tuberculosis, 2015
The diagnosis of pleural effusion is still difficult. The presence of pleural effusion can be confirmed by radiological studies including simple chest radiography, ultrasonography, or computed tomography.
K.E. Sobhey, B.A. Naglaa
doaj   +1 more source

Management of malignant pleural effusions [PDF]

Thorax, 2000
Malignant pleural effusion is a common problem in respiratory medicine and oncology and in some series accounts for up to 50% of all pleural effusions.1 2 The median survival following diagnosis ranges from three to 12 months and is largely dependent upon the underlying malignancy.
G Antunes, E Neville
openaire   +3 more sources

Malignant pleural effusion: from bench to bedside

European Respiratory Review, 2016
Malignant pleural effusion (MPE) is a common but serious condition that is related with poor quality of life, morbidity and mortality. Its incidence and associated healthcare costs are rising and its management remains palliative, with median survival ...
I. Psallidas, I. Kalomenidis, J. Porcel, B. Robinson, G. Stathopoulos   +4 more
semanticscholar   +1 more source