Results 241 to 250 of about 105,788 (296)

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, Volume 13, Issue 35, 24 June 2026.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

The role of the pleural fluid lactate dehydrogenase/adenosine deaminase ratio in differentiating between tuberculosis pleural effusion and parapneumonic effusion: a retrospective cohort study and meta-analysis. [PDF]

J Thorac Dis
Shi XY, Zhang YX, Dong SF, Chen QY, Yi FS.   +4 more
europepmc   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, Volume 13, Issue 31, 4 June 2026.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Brown-Colored Malignant Pleural Fluid With High Bilirubin Levels: A Case Series. [PDF]

Case Rep Pulmonol
Huan NC, Nyanti LE, Lee XY, Ramarmuty HY, Eng DTS, Sivaraman Kannan KK, Gary Lee YC.   +6 more
europepmc   +1 more source

Pleural fluid characteristics of patients with COVID-19 infection. [PDF]

Clin Respir J
Denu RA, Forth V, Shafiq M.
europepmc   +1 more source

Influence of age and sex on the diagnostic accuracy of pleural fluid carcinoembryonic antigen for malignant pleural effusion: a <i>post hoc</i> analysis. [PDF]

Front Oncol
Yang DN, Wen JX, Niu Y, Hai L, Yang Q, Cha SN, Yan C, Zhu HZ, Jiang TW, Yan L, Huang JH, Chen H, Zuo XR, Zheng WQ, Hu ZD.   +14 more
europepmc   +1 more source

Clinical Images: Thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly syndrome presenting as bilateral adrenal hemorrhage

ACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Masaki Itagane, Mitsuyo Kinjo
wiley   +1 more source

Pleural fluid proteomics from patients with pleural infection shows signatures of diverse neutrophilic responses: The Oxford Pleural Infection Endotyping Study (TORPIDS-2). [PDF]

Eur Respir J
Kanellakis NI, Antoun E, Cano-Gamez K, Chu J, Manoharan N, Berridge G, Vendrell I, Zhang Z, Corcoran JP, Elsheikh A, Dong T, Fischer R, Whalley JP, Knight JC, Rahman NM.   +14 more
europepmc   +1 more source

Beyond the Milky Pleural Fluid: A 14-Year Study on Non-Traumatic Chylothorax From a Tertiary Care Hospital in India. [PDF]

Cureus
Basha AK, Prakash A, Singh KK, Prajapat D, Talwar D, Talwar D.   +5 more
europepmc   +1 more source