Results 71 to 80 of about 2,617,227 (385)

Identifying Malignant Pleural Effusion by A Cancer Ratio (Serum LDH: Pleural Fluid ADA Ratio)

open access: yesLung, 2015
AimWe studied the diagnostic potential of serum lactate dehydrogenase (LDH) in malignant pleural effusion.MethodsRetrospective analysis of patients hospitalized with exudative pleural effusion in 2013.ResultsSerum LDH and serum LDH: pleural fluid ADA ...
Akash Verma   +2 more
semanticscholar   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

The Role of Pleural Fluid Procalcitonin in the Differential Diagnosis of Parapneumonic Pleural Effusions and its Relation with Pleural Fluid Ultrasound

open access: yesSouthern Clinics of Istanbul Eurasia, 2020
INTRODUCTION[|]Procalcitonin (PCT) is a highly specific marker for the detection of infectious diseases. In recent years, studies on this marker have been conducted in patients with pleural fluid.
Bülent Akkurt   +5 more
doaj   +1 more source

Incidence, outcomes, and risk factors of pleural effusion in patients receiving dasatinib therapy for Philadelphia chromosome-positive leukemia. [PDF]

open access: yes, 2019
Dasatinib, a second-generation BCR-ABL1 tyrosine kinase inhibitor, is approved for the treatment of chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia, both as first-line therapy and after imatinib intolerance or ...
Abruzzese, Elisabetta   +10 more
core   +2 more sources

Microbiome profile associated with malignant pleural effusion. [PDF]

open access: yes, 2020
INTRODUCTION:There is ongoing research into the development of novel molecular markers that may complement fluid cytology malignant pleural effusion (MPE) diagnosis.
Gilbert, Jack A   +5 more
core   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

open access: yesAdvanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey   +6 more
wiley   +1 more source

Advances in imaging chest tuberculosis: blurring of differences between children and adults [PDF]

open access: yes, 2009
This article reviews the ongoing role of imaging in the diagnosis of tuberculosis (TB) and its complications. A modern imaging classification of TB, taking into account both adults and children and the blurring of differences in the presentation patterns,
Ahmad   +63 more
core   +2 more sources

Pleural fluid tumour markers in malignant pleural effusion with inconclusive cytologic results.

open access: yesCurrent Oncology, 2015
BACKGROUND The presence of tumour cells in pleural fluid or tissue defines an effusion as malignant. Cytology analysis of the pleural fluid has about 60% diagnostic sensitivity.
L. Antonangelo   +5 more
semanticscholar   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

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