Results 31 to 40 of about 115,025 (142)
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley +1 more source
Mortality from Pleural and Lung Cancer in Railway Maintenance Workers [PDF]
Background: Occupational exposure to asbestos remains a significant public health concern due to its association with pleural cancer and other cancers.
Caraballo Arias, Yohama Auxilladoras +10 more
core +2 more sources
ABSTRACT Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder that affects multiple organ systems, most commonly the skin, peripheral nerves, and skeletal system. However, involvement of the anterior mediastinum is rare and has been sporadically reported in the literature.
Yuhao Qi +4 more
wiley +1 more source
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening, exceedingly rare hyperinflammatory syndrome that typically presents with nonspecific symptoms such as fever and cytopenia. An early diagnosis of HLH is a significant clinical challenge, especially in children with presentations mimicking common infectious diseases.
Muhammad Taaha Siddiqui +4 more
wiley +1 more source
Cancer‐related pain: A bidirectional modulator of cancer progression
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He +5 more
wiley +1 more source
Immune‐Related Encephalitis in a Patient With Pleural Mesothelioma: Case Report
Immune‐related encephalitis is a rare condition characterized by nonspecific symptoms and often minimal abnormal findings on examination. Optimal management of immune‐related encephalitis needs to be established. ABSTRACT A 69‐year‐old man who was a former plumber with a history of occupational asbestos exposure was diagnosed with unresectable pleural ...
Fumie Onishi +6 more
wiley +1 more source
Derrame Pleural Infeccioso. [PDF]
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Tocoginecologia, Curso de Medicina, Florianópolis ...
Spillere, José Carlos
core
Update on the Pathophysiology, Aetiology and Management of Central Sleep Apnoea
ABSTRACT Central sleep apnoea (CSA) of the periodic breathing type occurs during the transition between wakefulness and stage 1 and 2 non‐REM sleep. In adults at sea level, it occurs most commonly due to advanced heart failure (HF) or chronic opioid use and in ~5% of obstructive sleep apnoea patients initiating CPAP.
Sahan D. Chandrasekara +1 more
wiley +1 more source
The experience of mesothelioma in Northern England [PDF]
Mesothelioma is a potentially preventable fatal disease causing almost 2000 deaths/year in the UK, increasing in incidence, and lacking effective treatments.
Clayson, Helen
core +4 more sources
Derrame pleural parapneumônico: análise de 271 casos. [PDF]
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Cavalheiro, André Gustavo Castioni
core

