Results 111 to 120 of about 377 (211)

Extracellular fluid viscosity influences the mechanics and migration of MDA‐MB‐231 cells in a macromolecule‐dependent manner

open access: yesThe FEBS Journal, EarlyView.
Macromolecule‐dependent increases in extracellular fluid viscosity alter cell phenotype. These distinct macromolecules create different extracellular environments that modulate cell morphology and mechanoprotein expression, migration and invasion capacity, and cellular mechanical properties.
Ian M. Smith   +6 more
wiley   +1 more source

Proteomic Analysis of Serum Extracellular Vesicles Revealed Fibulin‐3 as a Novel Predictive Biomarker for Hepatocellular Carcinoma in Patients With Chronic Hepatitis B

open access: yesHepatology Research, EarlyView.
We carried out proteomic analysis of serum extracellular vesicles to identify biomarkers predictive of hepatocellular carcinoma (HCC) development in patients with chronic hepatitis B receiving nucleos(t)ide analog therapy. Candidate proteins identified through proteomic analysis were subsequently quantified in serum by ELISA.
Emi Sometani   +21 more
wiley   +1 more source

Clinical Outcomes of Gradual Corticosteroid Tapering for Immune Checkpoint Inhibitor‐Induced Liver Injury

open access: yesHepatology Research, EarlyView.
Patients with severe ICI‐induced liver injury are commonly treated with corticosteroids, but the optimal tapering strategy remains uncertain. In this study, a gradual corticosteroid tapering strategy based partly on Japanese clinical practice for autoimmune hepatitis was associated with a low rate of relapse and enabled many patients to safely resume ...
Naoto Soma   +7 more
wiley   +1 more source

Poorly differentiated lung adenocarcinomas with concurrent ALK and CD30 expression: a diagnostic pitfall mimicking ALK‐positive anaplastic large‐cell lymphoma

open access: yesHistopathology, EarlyView.
Poorly differentiated lung adenocarcinomas with concurrent anaplastic lymphoma kinase (ALK) and CD30 expression closely mimic ALK‐positive anaplastic large‐cell lymphoma, creating a significant diagnostic pitfall. Accurate classification requires comprehensive integration of clinical, radiologic, morphologic, immunophenotypic and molecular findings ...
Jietian Jin   +6 more
wiley   +1 more source

Unique Presentation of Metastatic Malignant Germ Cell Tumour Diagnosed on Pleural Effusion Cytology

open access: yes
Cytopathology, EarlyView.
Scarlet Brockmoeller   +3 more
wiley   +1 more source

Novel and emerging cutaneous soft tissue tumours

open access: yesHistopathology, EarlyView.
This review outlines the defining histopathological, immunophenotypic and molecular features of novel and emerging cutaneous soft tissue tumours, including hybrid superficial ALK‐rearranged myxoid spindle cell neoplasm/epithelioid fibrous histiocytoma, superficial neurocristic tumour, ALK‐rearranged epithelioid vascular neoplasm and MITF pathway ...
Saba Shafi, Josephine K Dermawan
wiley   +1 more source

Mast Cells in Host Defense Against Cutaneous Staphylococcus aureus Infection

open access: yesImmunology &Cell Biology, EarlyView.
Impact of S. aureus epicutaneous sensitization models on mast cell function in vivo. D. farinae and Staphylococcal enterotoxin B (SEB) activate Trpv1+ Tac1+ nociceptors to trigger the release of substance P (SP), which promotes mast cell degranulation through Mrgprb2. S.
Hannah Dychtenberg   +3 more
wiley   +1 more source

Legionella pneumophila pneumonia in South Eastern Sydney: diagnosis, prognosis and public health outcomes

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Legionellosis causes more severe disease than other aetiologies of community‐acquired pneumonia (CAP). Early recognition and treatment of Legionella pneumonia reduce mortality. Urinary antigen testing (UAT) has facilitated rapid and reliable diagnosis of Legionella pneumonia. Aims The aims of this study were as follows: (i) identify
Sue Qian   +9 more
wiley   +1 more source

Should TNF inhibitors be avoided in psoriasis patients with latent tuberculosis?

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Fabià Torres‐Betato, Lluís Puig
wiley   +1 more source

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