Results 111 to 120 of about 65,843 (240)

Extracellular fluid viscosity influences the mechanics and migration of MDA‐MB‐231 cells in a macromolecule‐dependent manner

open access: yesThe FEBS Journal, EarlyView.
Macromolecule‐dependent increases in extracellular fluid viscosity alter cell phenotype. These distinct macromolecules create different extracellular environments that modulate cell morphology and mechanoprotein expression, migration and invasion capacity, and cellular mechanical properties.
Ian M. Smith   +6 more
wiley   +1 more source

The 2025 ATS/ERS update of the international multidisciplinary classification of the interstitial pneumonias: implications for the pathologist

open access: yesHistopathology, EarlyView.
This review highlights changes relevant to pathologists in the updated multidisciplinary classification of interstitial pneumonias. Changes include expansion beyond idiopathic disease, subclassification as interstitial (fibrotic vs non‐fibrotic) and alveolar filling disorders, expansion to include additional patterns (e.g.
Andrew G Nicholson   +7 more
wiley   +1 more source

4‐1BB Expression and Signaling Regulates MAIT Cell Activation and Effector Functions

open access: yesImmunology &Cell Biology, EarlyView.
4‐1BB is a highly expressed TNFRSF co‐stimulatory receptor on MAIT cells upon activation. Expression and signaling via 4‐1BB enhance activation and provide co‐stimulation, boosting MAIT cell effector responses to TCR‐mediated activation. ABSTRACT Mucosal associated invariant T (MAIT) cells are abundant unconventional T cells that recognize microbe ...
Lamichhane R   +8 more
wiley   +1 more source

Australian clinical practice guideline: diagnosis and treatment of idiopathic multicentric Castleman disease

open access: yesInternal Medicine Journal, EarlyView.
Abstract Idiopathic multicentric Castleman disease (iMCD) is a rare condition. The pathogenesis is incompletely understood; however, interleukin‐6 (IL‐6) is a major mediator. The clinical presentation is heterogeneous, from mild constitutional symptoms to severe multi‐organ failure.
Dipti Talaulikar   +16 more
wiley   +1 more source

Should TNF inhibitors be avoided in psoriasis patients with latent tuberculosis?

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Fabià Torres‐Betato, Lluís Puig
wiley   +1 more source

Perioperative Transfusion Trigger Score Versus Restrictive Transfusion in Older Non‐Cardiac Surgery Patients: A Multicenter Randomized Controlled Trial

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Restrictive transfusion (Hb < 7 g/dL) is recommended for most perioperative patients, but the optimal threshold for those with cardiovascular disease or Hb 7–10 g/dL remains uncertain. The Perioperative Transfusion Trigger Score (POTTS), which integrates adrenaline requirement, FiO2, temperature, and angina history, may standardize ...
Shucong Liang   +9 more
wiley   +1 more source

Localised malignant mesothelioma presenting as an esophageal mass: An unusual manifestation. [PDF]

open access: yesRadiol Case Rep
Yaxley KL   +4 more
europepmc   +1 more source

Generalized Joint Hypermobility in Adolescent Idiopathic Scoliosis: Greater Curve Flexibility, Larger Thoracic Kyphosis, but Higher Complication Risk

open access: yesOrthopaedic Surgery, EarlyView.
Generalized joint hypermobility in adolescent idiopathic scoliosis is linked to greater spinal flexibility and increased thoracic kyphosis, but also elevates the risk of surgical complications, despite no significant differences in patient‐reported outcomes.
Di Liu   +5 more
wiley   +1 more source

Histomorphological and Immunohistochemical Analysis of Pleural Neoplasms.

open access: yesIranian journal of pathology
Primary pleural neoplasms are rare entities compared with the pleural involvement by metastatic carcinoma.The current study aimed at investigating the complete spectrum of pleural neoplasms and differentiating between them with the aid of immunohistochemistry (IHC).Consecutive pleural biopsy specimens positive for a neoplasm, both primary and ...
Sandhya, Venkatachala   +3 more
openaire   +1 more source

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