Results 171 to 180 of about 63,407 (297)

Extramedullary Disease—Achilles Heel in Myeloma?

open access: yesAmerican Journal of Hematology, Volume 101, Issue 3, Page 521-536, March 2026.
ABSTRACT Despite advances in therapy, extramedullary disease (EMD) remains an aggressive form of multiple myeloma associated with poor outcomes. Patients with true EMD, in which plasmacytomas have become completely independent of bone, have a particularly poor prognosis. The pathogenesis of EMD is driven by complex mechanisms involving loss of adhesion
Shaji Kumar   +7 more
wiley   +1 more source

Detecting FR‐⍺ Expression Level in Cytology Effusion Specimens From Ovarian Cancer and Comparing It With Tissue Specimens

open access: yesDiagnostic Cytopathology, Volume 54, Issue 3, Page 197-205, March 2026.
ABSTRACT Background Folate receptor‐⍺ (FR‐⍺) is an attractive target for targeted therapy. Mirvetuximab soravtansine (MIRV) has been approved by the United States Food and Drug Administration (FDA) for treating adult patients with FR‐⍺ positive, platinum‐resistant epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. Therefore,
Yadan Ma   +5 more
wiley   +1 more source

Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva   +9 more
wiley   +1 more source

Human Milk–Derived Peptide MAMP‐1 Ameliorates Sepsis‐Associated Acute Lung Injury in Mice Through APOA4 and the TLR4/NF‐κB Signaling Pathway

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
The study found that MAMP‐1 can alleviate lung injury by modulating the TLR4 signaling pathway to suppress LPS‐induced inflammation and promote cholesterol reverse transport. ABSTRACT Sepsis‐associated acute lung injury (SALI) significantly jeopardizes the health and survival prospects of neonates.
Shimei Lu   +8 more
wiley   +1 more source

Evaluating distant recurrence‐free survival and location of metastasis in HER2+ breast cancer by ER status

open access: yesInternational Journal of Cancer, Volume 158, Issue 5, Page 1184-1192, 1 March 2026.
What's New? The prognostic significance of the presence or absence of human epidermal growth factor receptor 2 (HER2) and estrogen receptor (ER) in breast cancer is well‐established. However, the relationship of HER2 and ER with distant disease recurrence and metastasis location is less well understood.
Damien Kaukonen   +4 more
wiley   +1 more source

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem   +9 more
wiley   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang   +7 more
wiley   +1 more source

Histological and Immunohistochemical Characterization of a Histiocytic Sarcoma Associated With a Follicular Lymphoma in a Ring‐tailed Lemur (Lemur catta)

open access: yesVeterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Histological and Immunohistochemical Characterization of a Histiocytic Sarcoma Associated with a Follicular Lymphoma in a Ring‐tailed Lemur (Lemur catta). Nicolás Aradilla, Rocío Canales, Teresa Lorenzo‐Bermejo, Mireia Mainez, Jordi Aguiló‐Gisbert, David Marbella, Javier María De Pablo‐Moreno and Antonio Rodríguez‐Bertos.
Nicolás Aradilla   +7 more
wiley   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for WHO CNS5 adult‐type diffuse gliomas

open access: yesBrain Pathology, Volume 36, Issue 2, March 2026.
ADAPTR recommendations for Adult‐type Diffuse Gliomas in Resource‐restrained settings. Abstract The fifth edition of the WHO classification of CNS Tumors (WHO CNS5) has revised the diagnostic and grading criteria for Adult‐type Diffuse Gliomas (ADGs) by integrating molecular parameters with histologic features.
Vani Santosh   +11 more
wiley   +1 more source

Restricted Expression of the Constant Region 1 of T‐Cell Receptor β by Flow Cytometry Facilitates Detection of T‐Cell Neoplasms With High Specificity but Moderate Predictive Value

open access: yesEuropean Journal of Haematology, Volume 116, Issue 3, Page 245-255, March 2026.
ABSTRACT Objectives To determine the diagnostic value of disclosing monotypic T‐cell populations by expression analysis of the constant region 1 of T‐cell receptor β (TRBC1) by flow cytometry, for the detection of T‐cell neoplasms, in a routine hematopathology practice setting.
Nilofar Rajabian   +4 more
wiley   +1 more source

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