Results 181 to 190 of about 44,445 (364)

Comparative Survival Analysis of Anti‐Angiogenic Agent Plus Immunochemotherapy in NSCLC Patients After Frontline EGFR‐TKI Treatment: A Retrospective Cohort Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Advanced‐stage EGFR‐mutated lung non‐small cell lung cancer (NSCLC) challenges current treatment paradigms, particularly after frontline EGFR‐TKI therapy failure. This study investigates the survival impact of combined anti‐angiogenic agent and immunochemotherapy (AICT) for this population.
Yi‐Tse Su   +6 more
wiley   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi   +2 more
wiley   +1 more source

Expert Consensus on the Diagnosis and Treatment of Malignant Pericardial Mesothelioma

open access: yesMed Research, EarlyView.
ABSTRACT Primary malignant pericardial mesothelioma (PMPM), a rare pericardium‐derived malignancy, urgently requires standardized diagnostic and therapeutic protocols. This consensus, established by the Chinese Alliance of Research for Mesothelioma (ChARM) through the integration of evidence‐based research and multicenter clinical expertise, addresses ...
Qing Ji   +112 more
wiley   +1 more source

Optimized Dynamic Network Biomarker Deciphers a High‐Resolution Heterogeneity Within Thyroid Cancer Molecular Subtypes

open access: yesMed Research, EarlyView.
An optimized dynamic network biomarker approach reveals a critical transition signal and identifies three distinct molecular subtypes of differentiated thyroid cancer, each with unique global regulatory landscapes. ABSTRACT The progression of differentiated thyroid carcinoma (DTC) poses significant clinical challenges, especially in determining the ...
Haonan Zhang   +20 more
wiley   +1 more source

Interplay‐robust optimization for treating irregularly breathing lung patients with pencil beam scanning

open access: yesMedical Physics, EarlyView.
Abstract Background The steep dose gradients obtained with pencil beam scanning allow for precise targeting of the tumor but come at the cost of high sensitivity to uncertainties. Robust optimization is commonly applied to mitigate uncertainties in density and patient setup, while its application to motion management, called 4D‐robust optimization ...
Ivar Bengtsson   +3 more
wiley   +1 more source

Thorax‐encompassing multi‐modality PET/CT deep learning model for resected lung cancer prognostication: A retrospective, multicenter study

open access: yesMedical Physics, EarlyView.
Abstract Background Patients with early‐stage non‐small cell lung cancer (NSCLC) typically receive surgery as their primary form of treatment. However, studies have shown that a high proportion of these patients will experience a recurrence after their resection, leading to an increased risk of death.
Jaryd R. Christie   +11 more
wiley   +1 more source

Pleura-Based Lipomatous Neoplasm with RUNX1T1::PLAG1 Rearrangement and RB1 Gene Deletion

open access: yesHuman Pathology Reports
Background: Lipoblastoma is a benign tumor arising from embryonic white fat, commonly observed in infancy and early childhood. It manifests in two pathologically identical forms: circumscribed and diffuse. Typically, it is found in the extremities, trunk,
Rayan Sibira   +5 more
doaj  

Diagnotic Value of the Combined Determination of Telomerase Activity in Induced Sputum, Pleural Effusion and Fiberobronchoscopic Biopsy Samples in Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2010
Background and objective It has been proven that telomerase activation correlates with the carcinogenesis, aggressiveness and turnover of lung cancer.
Guangzhen LIU   +4 more
doaj  

Efficacy of High‐Dose Intravenous Anakinra in Pediatric TAFRO Syndrome: Report of Two Cases and Literature Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly) syndrome is a rare, life‐threatening inflammatory condition linked to infections, neoplasms, and idiopathic multicentric Castleman disease. Interleukin (IL)‐6 inhibitors are the primary treatment, but refractory cases require alternatives. This
Serena Palmeri   +10 more
wiley   +1 more source

Malignant Peripheral Nerve Sheath Tumor in Children and Adolescents: Local Treatment in a Retrospective Single‐Center Experience

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Malignant peripheral nerve sheath tumor (MPNST) is a rare and aggressive sarcoma often associated with neurofibromatosis type 1, whose clinical management remains complex and challenging. Few publications exist on pediatric MPNST, and limited data are available on the best treatment approach, in particular regarding local therapy ...
Andrea Ferrari   +24 more
wiley   +1 more source

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