Results 31 to 40 of about 377 (211)

Predominantly Fibrous Malignant Mesothelioma in a Cat

Veterinary Medicine International, 2010
Malignant mesotheliomas are rare tumours in domestic cats. They occur within the abdominal or thoracic cavity and are regularly associated with pleural or peritoneal effusions.
Alexander Th. A. Weiss, Afonso B. da Costa, Robert Klopfleisch   +2 more
doaj   +1 more source

Stromal‐Derived IL‐8 Promotes M2 Macrophage Polarization via the RhoA/MRTF‐A/SRF Transcriptional Axis to Impair CD8+ T Cell Cytotoxicity in Lung Cancer

Advanced Science, EarlyView.
In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu, Qiyu Fang, Jia Yu, Ting Yu, Huashan Shi, Kaiqi Jin, Lei Jiang, Wentian Zhang   +7 more
wiley   +1 more source

Surgical resection of pleural lipoma after 9 years of serial imaging

Journal of Cardiothoracic Surgery
Pleural lipomas are rare benign intrathoracic mesenchymal neoplasms. Although typically asymptomatic, they can enlarge and cause symptoms secondary to compression of surrounding intrathoracic structures.
Chadi Nahal, Chetna Purohit, Andrew Toma, Peter Seirafi   +3 more
doaj   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Systematic Review and Meta‐Analysis on the Efficacy and Safety of Salvage Esophagectomy for T4 Esophageal Squamous Cell Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
This meta‐analysis of 208 cases shows that salvage esophagectomy for cT4 esophageal squamous cell carcinoma achieves a 72% R0 resection rate, offering a curative pathway for selected patients. However, it remains a high‐risk procedure with an 18% anastomotic leak rate and 30% major complications (Clavien–Dindo ≥ III).
Makoto Sakai, Kengo Kuriyama, Kazue Nagai, Ken Shirabe, Hiroshi Saeki   +4 more
wiley   +1 more source

Perioperative Challenges and Anaesthetic Management in Video-assisted Radical Thymectomy with Pleurectomy and Hyperthermic Intrathoracic Chemotherapy - A Case Report

Journal of Onco-Anaesthesiology and Perioperative Medicine
Thymoma is a rare anterior mediastinal tumour that arises from thymic epithelial cells. It accounts for
Shiladitya Bose, Arghya Mukerjee, Sayantan Saha, TG Arun Gopan   +3 more
doaj   +1 more source

Mortality trends of cardiac, mediastinal and pleural malignancies in the United States, 1999–2020: a population-based analysis of demographic and geographic disparities

Frontiers in Oncology
BackgroundCardiac, mediastinal, and pleural malignancies represent rare but clinically significant thoracic neoplasms. Despite their clinical importance, comprehensive epidemiological analyses of mortality trends for these tumors remain limited.
Wenlong Ding, Fachao Shi, Siyun Li, Siwen Xue, Cunming Fang, Caoyang Fang   +5 more
doaj   +1 more source

Dyspnoea and restrictive lung disease due to mediastinal and pleural lipomatosis in morbid obesity

Respirology Case Reports, 2019
Dyspnoea in obese patients can be multifactorial and complex. Mediastinal and pleural lipomatosis can be associated with obesity and is usually considered asymptomatic and benign. We report an obese 39‐year‐old man who presented with progressive dyspnoea,
Jen Yuh Lim, Kim A. McAnulty, Catherina L. Chang   +2 more
doaj   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Posthumously Diagnosed Myhre Syndrome Presenting With Pleural Remodeling and Endometrial Cancer

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (OMIM 139210) is a genetic condition defined by neurodevelopmental disability, characteristic facial features, and multisystem proliferative fibrosis. While various types of lung disease have been reported, pleural remodeling leading to restrictive lung disease has not yet been described.
Jeanette Saffir, Karee Morgan, Karigynn Chaimson, Blake E. Funke, Kim L. Sandler, Melissa Hogan, Thomas Cassini   +6 more
wiley   +1 more source