Results 71 to 80 of about 377 (211)

Ginsenoside Rg1 Ameliorates LPS‐Induced Sepsis‐Associated Lung Injury in Mice via VEGFC/D‐VEGFR3 Signaling‐Mediated Lymphangiogenesis and Lymphatic Remodeling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang, Lan Hu, Chun‐Pan Zhang, Wen‐Jie Qi, Yu‐Guo Song   +4 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

The Frequency of Various Diseases in Patients Presenting with Pleural Effusion

Gomal Journal of Medical Sciences, 2013
Background: Pleural effusion is a common diagnostic problem. Successful treatment of these cases depends upon establishing the exact etiology. The objective of this study was to determine the frequency of clinical features and frequency of various ...
Muhammad Rehan, Muhammad Tanveer Alam, Khalid Imran, Syed Zea-Ul-Islam Farrukh, Muhammad Masroor, Pawan Kumar   +5 more
doaj  

Clinical and Molecular Features of BAP1‐Mutated Meningiomas: Case Series

Molecular Carcinogenesis, EarlyView.
ABSTRACT BRCA1‐associated protein 1 (BAP1)‐deficient meningiomas represent a clinically and molecularly distinct subgroup with variable histology and aggressive behavior that may not be fully captured by current grading criteria. The clinical spectrum of BAP1 alterations in meningiomas, including both somatic and germline contexts, remains incompletely
Ivan Pradilla, Rasha Alfattal, Susan L. McGovern, Shaan M. Raza, Franco DeMonte, Leomar Y. Ballester, Chirag B. Patel, Carlos Kamiya‐Matsuoka   +7 more
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Pleural pseudomyxoma secondary to appendiceal mucinous adenocarcinoma: a case report

Case Reports in Oncology
Introduction: Appendiceal mucinous neoplasms are uncommon gastrointestinal tumors. In some cases, they evolve into pseudomyxoma peritonei (PMP), a condition characterized by mucinous ascites and peritoneal dissemination.
Mohammad Hossein Teymoori, Alireza Gandomi-Mohammadabadi, Alireza Ramezani, Nasrin Asgari Soran, Masoud Maleki, Massoud Baghai Wadji   +5 more
doaj   +1 more source

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Adenocarcinoma Lung Presenting with Bilateral Chylothorax and SVC Thrombosis

Journal of Association of Pulmonologist of Tamil Nadu, 2018
Chylothorax is a rare clinical entity characterized by a milky white fluid within the pleural space. It is a rare condition in which damage or obstruction of the thoracic duct results in chyle leakage into the pleural space.
S Aneeshkumar, R Narasimhan, C Srirajani
doaj  

Pleural Rosai-Dorfman disease complicated with renal clear cell carcinoma: a case report and literature review

Frontiers in Oncology
BackgroundRosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare non-malignant disorder characterized by excessive proliferation of histiocytes, the cause of which remains unknown.
Sudan Tang, Sudan Tang, Xinju Yang, Shunan Wang, Shunan Wang, Qin Xiao, Qin Xiao   +6 more
doaj   +1 more source

Management of Refractory Thymoma‐Associated Myasthenia Gravis With Sequential FcRn Antagonist and Complement Inhibition Combined With Resection of Pleural Dissemination

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Myasthenia gravis (MG) associated with disseminated thymoma is often refractory to conventional treatments due to continuous autoantibody production. The optimal treatment strategy, particularly the combination of complement component 5 (C5) inhibitor, neonatal Fc receptor (FcRn) antagonist, and surgical resection in thymoma‐associated ...
Hiroyuki Takenaka, Madoka Iida, Yuki Fukami, Masahisa Katsuno   +3 more
wiley   +1 more source