Results 181 to 190 of about 2,581,392 (247)

Clinical and Molecular Features of BAP1‐Mutated Meningiomas: Case Series

Molecular Carcinogenesis, Volume 65, Issue 10, Page 1343-1350, October 2026.
ABSTRACT BRCA1‐associated protein 1 (BAP1)‐deficient meningiomas represent a clinically and molecularly distinct subgroup with variable histology and aggressive behavior that may not be fully captured by current grading criteria. The clinical spectrum of BAP1 alterations in meningiomas, including both somatic and germline contexts, remains incompletely
Ivan Pradilla, Rasha Alfattal, Susan L. McGovern, Shaan M. Raza, Franco DeMonte, Leomar Y. Ballester, Chirag B. Patel, Carlos Kamiya‐Matsuoka   +7 more
wiley   +1 more source

Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management

MedComm, Volume 7, Issue 10, October 2026.
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley   +1 more source

Improvements With Tiotropium Maintenance Therapy in COPD Patients Without Dyspnea

MedComm, Volume 7, Issue 10, October 2026.
In a post hoc analysis of the Tie‐COPD trial, including 305 patients with mild‐to‐moderate COPD and no dyspnea (mMRC 0), 2 years of tiotropium improved lung function, lowered the annual exacerbation rate, and delayed the first clinically important deterioration, indicating benefit beyond symptom relief in a group not currently offered maintenance ...
Zihui Wang, Junfeng Lin, Guannan Cai, Fan Wu, Zhishan Deng, Qi Wan, Gaoying Tang, Cuiqiong Dai, Lifei Lu, Kunning Zhou, Xiaohui Wu, Suyin Huang, Fangyan Wu, Nanshan Zhong, Yumin Zhou, Pixin Ran   +15 more
wiley   +1 more source

First line medical thoracoscopy in undiagnosed pleural effusion.

reservedBackground: il versamento pleurico non spiegato rimane un frequente problema clinico. Le attuali linee guida internazionali descrivono un percorso diagnostico standard in cui la toracoscopia medica viene considerata dopo una fase iniziale di ...
CAPPOZZO, MARCO
core  

Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta, Ramakrishna Vadde, Ganji Purnachandra Nagaraju   +2 more
wiley   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Myasthenia Gravis and Thymoma

Muscle &Nerve, Volume 74, Issue 4, Page 1156-1173, October 2026.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Effects of Adding Incentive Spirometry to Hospital‐Based Cardiovascular Rehabilitation on Pulmonary Complications, Hospital Length of Stay, and Clinical‐Functional Recovery After Cardiac Surgery: A Randomized Controlled Trial

Physiotherapy Research International, Volume 31, Issue 4, October 2026.
ABSTRACT Background and Purpose This study investigated the effects of combining incentive spirometry with cardiac rehabilitation compared with cardiac rehabilitation alone on postoperative pulmonary complications, clinical‐functional recovery, and hospital length of stay in patients undergoing cardiac surgery.
Bruna Elise da Silva Messias, Thamires Alessandra Silveira da Silva, Rafaela Anversa Schreiner, Letícia Torres, Jéssica Bischoff, Taís Flores de Oliveira, Vinicius Peringer, Francine Manara Bortagarai, Mateus Diniz Marques, Bruna Eibel, Carine Cristina Callegaro   +10 more
wiley   +1 more source

Post-cardiac Surgery Pleural Effusion and the Overlooked Importance of the Diaphragm: Setting Up an Inspiratory Training Program Correctly. [PDF]

Cureus
Bordoni B, Morabito B, Escher AR.
europepmc   +1 more source

Pneumomediastinum and Subcutaneous Emphysema After Rapid Mediastinal Mass Regression

eJHaem, Volume 7, Issue 5, October 2026.
Fahad Alsayed, Ailish Coblentz, Oussama Abla   +2 more
wiley   +1 more source