Results 61 to 70 of about 2,581,392 (247)

Impact of pleural manometry in predicting non-expandable lung: a prospective study

The Egyptian Journal of Bronchology
Background Pleural manometry provides a real-time assessment of pleural pressure during thoracentesis and may aid in identifying non-expandable lung (NEL). Its diagnostic value relative to conventional pleural fluid biomarkers remains unclear.
Hany Hussein Moussa, Mohamed Mostafa Elsheikh, Noha Elsayed Mohamed, Walaa M. Eid   +3 more
doaj   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Pleural pressure swing and lung expansion after malignant pleural effusion drainage: the benefits of high-temporal resolution pleural manometry

, 2013
BackgroundMalignant pleural effusion is a common complication in end-stage cancer patients and can cause severe dyspnea. Therapeutic thoracentesis is often limited to 1 to 1.5 L.
Goldfinger, V., Vincent, A., Faraq, S., Boshuizen, R., Sinaasappel, M., van den Heuvel, M.   +5 more
core   +1 more source

An echocardiographic assessment of cardiovascular hemodynamics in patients with large pleural effusion

Indian Heart Journal, 2013
Background: The close relationship between pleural space and pericardial space and the dependence of their pressure kinetics are well known. This study evaluates the effects of increased intra pleural pressure due to pleural effusion on cardiovascular ...
Sundar Chidambaram, Venkatesan Sangareddi, Gnanavelu Ganesan, V.E. Dhandapani, M.S. Ravi, K. Meenakshi, D. Muthukumar, N. Swaminathan, G. Ravishankar   +8 more
doaj   +1 more source

Additional work of breathing from trigger errors in mechanically ventilated children

Respiratory Research, 2020
Background Patient–ventilator asynchrony is associated with increased morbidity and mortality. A direct causative relationship between Patient–ventilator asynchrony and adverse clinical outcome have yet to be demonstrated.
Robert G. T. Blokpoel, Alette A. Koopman, Jefta van Dijk, Martin C. J. Kneyber   +3 more
doaj   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Subatmospheric pressure in the rabbits pleural lymphatics

, 1999
1. Hydraulic pressure in intercostal and diaphragmatic lymphatic vessels was measured through the micropuncture technique in 23 anaesthetised paralysed rabbits.
Daniela Negrini, Massimo Del Fabbro, M. DEL FABBRO, NEGRINI, DANIELA, D. Negrini   +4 more
core   +1 more source

A novel pleural-bladder pump for the management of recurrent malignant pleural effusions: a feasibility animal study

Respiratory Research, 2020
Background Recurrent malignant pleural effusions (MPE) are common and associated with significant morbidity in cancer patients. A new pump connecting the pleural cavity and the bladder may have application for the management of recurrent MPE.
S. Laroumagne, J. Guinde, S. Berdah, H. Dutau, J. Capel, P. Astoul   +5 more
doaj   +1 more source

Chiari I Malformation: Review and Update of Current Treatment Options

Clinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo, Shuhei Shiino, Stephen Z. Shapiro, Brianna L. Hines, Noritaka Komune, Carmine Antonio Donofrio, Filippo Badaloni, Antonio Fioravanti, Joseph Lockwood, C. J. Bui, Aaron S. Dumont, R. Shane Tubbs   +11 more
wiley   +1 more source

Derrame Pleural Infeccioso. [PDF]

, 1980
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Tocoginecologia, Curso de Medicina, Florianópolis ...
Spillere, José Carlos
core