Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial [PDF]
IMPORTANCE For treatment of malignant pleural effusion, nonsteroidal anti-inflammatory drugs (NSAIDs) are avoided because they may reduce pleurodesis efficacy.
Ali, N+32 more
core +2 more sources
Protocol of the Australasian Malignant Pleural Effusion (AMPLE) trial: a multicentre randomised study comparing indwelling pleural catheter versus talc pleurodesis [PDF]
INTRODUCTION: Malignant pleural effusion can complicate most cancers. It causes breathlessness and requires hospitalisation for invasive pleural drainages. Malignant effusions often herald advanced cancers and limited prognosis.
Bint, M+15 more
core +1 more source
The efficacy of indwelling pleural catheter placement versus placement plus talc sclerosant in patients with malignant pleural effusions managed exclusively as outpatients (IPC-PLUS): study protocol for a randomised controlled trial [PDF]
BACKGROUND: Malignant pleural effusions (MPEs) remain a common problem, with 40,000 new cases in the United Kingdom each year and up to 250,000 in the United States.
Bhatnagar, R+6 more
core +5 more sources
Primary pneumothorax: Should surgery be offered after the first episode? [PDF]
published_or_final_versio
Sihoe, DLA, Yeung, JWL, Yu, SYP
core +1 more source
Cost-effectiveness of indwelling pleural catheter compared with talc in malignant pleural effusion [PDF]
BACKGROUND AND OBJECTIVE: Malignant pleural effusion is associated with morbidity and mortality. A randomized controlled trial previously compared clinical outcomes and resource use with indwelling pleural catheter (IPC) and talc pleurodesis in this ...
Davies, HE+8 more
core +3 more sources
Advanced medical interventions in pleural disease [PDF]
The burden of a number of pleural diseases continues to increase internationally. Although many pleural procedures have historically been the domain of interventional radiologists or thoracic surgeons, in recent years, there has been a marked expansion ...
Astoul, Philippe+6 more
core +2 more sources
Inflammatory parameters after pleurodesis in recurrent malignant pleural effusions and their predictive value [PDF]
Recurrent pleural malignant effusion is a common problem which can be treated by inducing symphysis of the pleural sheets. Many different drugs administered into the pleural space can be used to achieve this.
Agrenius, Veronica+4 more
core +1 more source
Managing malignant pleural effusion with an indwelling pleural catheter: factors associated with spontaneous pleurodesis [PDF]
published_or_final_versio
Ip, MSM+5 more
core +1 more source
Estimating past inhalation exposure to asbestos: a tool for risk attribution and disease screening [PDF]
Introduction: Late presentation is common in mesothelioma. Reliable assessment of past exposure to asbestos is a necessary first step for risk attribution and for the development of a future screening programme. Such a programme could maximise access
Blyth, Kevin G.+2 more
core +1 more source
Predictors of pleurodesis success [PDF]
Introduction: Patients with malignant pleural effusions (MPE) have a poor life expectancy and a high symptom burden. Definitive management strategies include chest drain and pleurodesis or placement of an indwelling pleural catheter. A meta analysis showed that 76% - 82% of patients had a successful pleurodesis with sterile talc. It has been postulated
Mercer, R+16 more
openaire +3 more sources