Results 121 to 130 of about 55,390 (242)

Histovariability and fossil diagenesis of Pissarrachampsa (Pseudosuchia, Notosuchia, Baurusuchidae) from the Upper Cretaceous of Southeast Brazil

open access: yesThe Anatomical Record, Volume 309, Issue 6, Page 1451-1463, June 2026.
Abstract Notosuchians were key components of western Gondwanan Cretaceous ecosystems in terrestrial predator niches and exhibited remarkable taxonomic and ecological diversity. Previous research has explored their physiology, metabolism, and histology, revealing varied growth patterns and life history strategies.
Tito Aureliano   +5 more
wiley   +1 more source

A Dynamic Change of Microglial States Occurs During the Transition From Photoreceptor Degeneration to Regeneration in Zebrafish pde6c Mutants

open access: yesGlia, Volume 74, Issue 6, June 2026.
Zebrafish pde6c mutants undergo photoreceptor degeneration from 5 dpf, but rods regenerate from 4 wpf. scRNA‐seq of retinal microglia reveals dynamic change of states between 5 dpf and 4 wpf. Two states emerge specifically during regeneration. ABSTRACT Microglia, brain‐resident immune cells, maintain brain homeostasis.
Darshini Ravishankar   +2 more
wiley   +1 more source

A Cross‐Disease Microglial Transcriptional Program Characterizes Neurodegeneration and Highlights SPP1 as a Biomarker

open access: yesGlia, Volume 74, Issue 6, June 2026.
Distinct microglial subpopulations are depicted, highlighting variations in gene expression and functional roles in response to specific disease conditions and the complexity of microglial activation and differentiation in neurodegeneration. ABSTRACT Microglial cells are key players in maintaining brain homeostasis and responding to pathological ...
Alessandro Palma   +6 more
wiley   +1 more source

Critical point drying of brain tissue for X‐ray phase‐contrast imaging

open access: yesJournal of Synchrotron Radiation, Volume 33, Issue 3, Page 759-768, May 2026.
X‐ray phase contrast tomography can efficiently image brain tissue at subcellular resolution. Critical point drying allows a gentle replacement of interstitial material by air, enhancing X‐ray phase contrast of the ultrastructural features.X‐ray phase‐contrast tomography can efficiently image brain tissue at subcellular resolution.
Safe Khan   +15 more
wiley   +1 more source

Diffuse plexiform neurofibroma [PDF]

open access: yesIndian Journal of Surgery, 2010
S Sujith, Kumar   +2 more
openaire   +2 more sources

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos   +16 more
wiley   +1 more source

Bilateral Giant Plexiform Neurofibromas In Neurofibromatosis Type 1

open access: yesIndian Journal of Dermatology, 2002
A single plexiform neurofibroma or two of any type are considered diagnostic of neurofibromatosis type 1 (NF). Plexiform neurofibromas are congenital and pathognomonic for NF-1.
Thappa D . M   +2 more
doaj  

Cell‐Type‐Dependent Metabolic Compensation Preserves Photoreceptor Survival Through Pyruvate Kinase Isoform Balance

open access: yesThe FASEB Journal, Volume 40, Issue 7, 15 April 2026.
We investigated the roles of PKM2, PKM1, and LDHA in retinal metabolism and structural integrity. In the normal retina, these enzymes are maintained at defined levels that support photoreceptor function. Rod‐specific deletion of LDHA, alone or with PKM2, caused age‐dependent degeneration, as PKM1 induction did not reach levels comparable to PKM2.
Ammaji Rajala   +3 more
wiley   +1 more source

Impact of obesity with impaired glucose tolerance on retinal degeneration in a rat model of metabolic syndrome. [PDF]

open access: yes, 2017
PurposeMetabolic syndrome (MetS) is associated with several degenerative diseases, including retinal degeneration. Previously, we reported on progressive retinal degeneration in a spontaneous obese rat (WNIN/Ob) model.
Ayyagari, Radha   +7 more
core  

Neuroma Plexiforme [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1913
openaire   +2 more sources

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