Results 41 to 50 of about 249,895 (355)

Delayed clearance of cerebrospinal fluid tracer from choroid plexus in idiopathic normal pressure hydrocephalus

Journal of Cerebral Blood Flow and Metabolism, 2019
Impaired clearance of amyloid-β from choroid plexus is one proposed mechanism behind amyloid deposition in Alzheimer's disease. The present study examined whether clearance from choroid plexus of a cerebrospinal fluid tracer, serving as a surrogate ...
P. Eide, L. Valnes, A. Pripp, K. Mardal, G. Ringstad   +4 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Distal Nerve Transfer for Opponensplasty in the Setting of High Median Nerve Injury: A Case Series

Advances in Orthopedics
Conclusion: In high median-nerve injury, early reconstructive intervention can prevent the thenar muscle atrophy and leads to prompt reinnervation and complete restoration of thenar function.
Mohammadreza Emamhadi, Mohammad Haghani Dogahe, Amirreza Emamhadi   +2 more
doaj   +1 more source

Coeliac Plexus Block [PDF]

Anaesthesia and Intensive Care, 1973
Coeliac plexus blocks have had a reasonable success rate (approximately 70 per cent) in the relief of the pain of carcinoma of the pancreas or upper abdominal malignancy and were helpful for pancreatitis and in some cases of inoperable arterial insufficiency.
A, Black, B, Dwyer
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

A controlled randomized clinical trial of the efficacy and safety of hyaluronidase as an adjuvant to bupivacaine in ultrasound-guided supraclavicular brachial plexus block

Al-Azhar Assiut Medical Journal
Background and aim Several adjuvants are used with local anesthetics in regional blocks such as supraclavicular brachial plexus block. The goal of this combination is to increase the anesthetic duration.
Mohamed A. Mahmoud, Mohamed B. Ibrahim, Osama H.l Ahmed, Mohammed A.-S. Abdo Abu Hatab   +3 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Biceps lasso loop and self-locking tenodesis alongside repair of rotator cuff tears: randomised controlled trial study protocol (BLAST 1)

BMJ Open
Introduction Pathology of the long head of the biceps tendon (LHBT) frequently accompanies rotator cuff tears, with tenotomy and tenodesis often being used to address this pathology. While meta-analyses report comparable functional outcomes between these
Michel P J van den Bekerom, Thibault Lafosse, Geert Alexander Buijze, Igor J Shirinskiy, Dries Boulidam, Arno A Macken   +5 more
doaj   +1 more source

Klotho controls the brain–immune system interface in the choroid plexus

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Global depletion of klotho accelerates aging, whereas klotho overexpression counteracts aging-related impairments. Why klotho is expressed at much higher levels in the choroid plexus than in other brain regions is unknown.
Lei Zhu, L. Stein, Daniel H. Kim, Kaitlyn Ho, Guimei Yu, Lihong Zhan, T. Larsson, L. Mucke   +7 more
semanticscholar   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source